Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18438966 | 1.00 | CTSK (0.43) | CTSKCTSSL3MBTL1KMT2APOLB | |
| SCHEMBL28620928 | 0.84 | ATM (0.39) | KMT2APOLBATMTDP1 | |
| SCHEMBL20710289 | 0.84 | L3MBTL1 (0.45) | CTSKL3MBTL1KMT2APOLBCYP1A2 | |
| SCHEMBL24204924 | 0.84 | L3MBTL1 (0.45) | CTSKL3MBTL1KMT2APOLBCYP1A2 | |
| SCHEMBL11785105 | 0.84 | L3MBTL1 (0.39) | L3MBTL1KMT2APOLBCYP1A2CYP2C9 | |
| SCHEMBL22309439 | 0.83 | CTSK (0.48) | CTSKCTSSPOLBCYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL15312451 | 0.82 | CTSK (0.44) | CTSKCTSSKMT2APOLBCYP1A2 | |
| SCHEMBL19471832 | 0.82 | GNPAT (0.39) | CTSKCTSSKMT2APOLBATM | |
| SCHEMBL17449759 | 0.81 | CTSK (0.61) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17369162 | 0.81 | CTSK (0.61) | CTSKCTSSCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025844-A1 | PHENYL UREA ANALOGS AS FORMYL PEPTIDE RECEPTOR 1 (FPR1) SELECTIVE AGONISTS | ALLERGAN, INC. | 2024-01-25 | — | — | US | disclosed |
| EP-3331897-B1 | PHENYL UREA ANALOGS AS FORMYL PEPTIDE RECEPTOR 1 (FPR1) SELECTIVE AGONISTS | ALLERGAN INC (US) | 2021-03-24 | — | — | EP | disclosed |
| EP-3331897-B1 | PHENYL UREA ANALOGS AS FORMYL PEPTIDE RECEPTOR 1 (FPR1) SELECTIVE AGONISTS | ALLERGAN INC (US) | 2021-03-24 | — | — | EP | disclosed |
| US-20200079729-A1 | PHENYL UREA ANALOGS AS FORMYL PEPTIDE RECEPTOR 1 (FPR1) SELECTIVE AGONISTS | ALLERGAN, INC. | 2020-03-12 | — | — | US | disclosed |
| EP-3331897-A1 | PHENYL UREA ANALOGS AS FORMYL PEPTIDE REPCEPTOR 1 (FPR1) SELECTIVE AGONISTS | ALLERGAN, INC. (US) | 2018-06-13 | — | — | EP | disclosed |
| WO-2017023907-A1 | PHENYL UREA ANALOGS AS FORMYL PEPTIDE REPCEPTOR 1 (FPR1) SELECTIVE AGONISTS | ALLERGAN, INC. (US) | 2017-02-09 | — | — | WO | disclosed |
| WO-2017023907-A1 | PHENYL UREA ANALOGS AS FORMYL PEPTIDE REPCEPTOR 1 (FPR1) SELECTIVE AGONISTS | ALLERGAN, INC. (US) | 2017-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200079729-A1 | PHENYL UREA ANALOGS AS FORMYL PEPTIDE RECEPTOR 1 (FPR1) SELECTIVE AGONISTS | FPR1, FPR2, FPR3 | CTSK 2536/4885CTSS 2358/4885L3MBTL1 4113/4885 |
| US-20240025844-A1 | PHENYL UREA ANALOGS AS FORMYL PEPTIDE RECEPTOR 1 (FPR1) SELECTIVE AGONISTS | FPR1, FPR2, FPR3 | CTSK 2536/4885CTSS 2358/4885L3MBTL1 4113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.