SCHEMBL22309883

SCHEMBL22309883

O=CC(=O)CCCC(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 2/20 0.61
LMNA P02545 4/20 0.53
TSHR P16473 4/20 0.50
NFKB1 P19838 2/20 0.50
PMP22 Q01453 1/20 0.50
CAMK2A Q9UQM7 1/20 0.46
GABRR3 A8MPY1 1/20 0.43
GABRP O00591 1/20 0.43
GABRD O14764 1/20 0.43
HDAC3 O15379 1/20 0.43
GABBR2 O75899 1/20 0.43
CYP1A2 P05177 1/20 0.43
THRB P10828 1/20 0.43
GABRA1 P14867 1/20 0.43
GABRB1 P18505 1/20 0.43
GABRG2 P18507 1/20 0.43
GABRR1 P24046 1/20 0.43
GABRB3 P28472 1/20 0.43
GABRR2 P28476 1/20 0.43
SLC6A1 P30531 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4801627 0.92 TSHR (0.63) SLC22A6LMNATSHRNFKB1PMP22
SCHEMBL14332654 0.92 TSHR (0.63) SLC22A6LMNATSHRNFKB1PMP22
SCHEMBL11678561 0.92 TSHR (0.63) SLC22A6LMNATSHRNFKB1PMP22
SCHEMBL27549664 0.87 SLC22A6 (0.46) SLC22A6LMNATSHRNFKB1PMP22
SCHEMBL7086929 0.82
SCHEMBL11451566 0.80 LMNA (0.53) SLC22A6LMNATSHRNFKB1PMP22
SCHEMBL4811015 0.79 HDAC3 (0.43) SLC22A6LMNATSHRNFKB1PMP22
Glutarate SCHEMBL22798941 0.79 SLC22A6 (0.73) SLC22A6LMNATSHRNFKB1PMP22
Glutarate SCHEMBL27542711 0.79 SLC22A6 (0.73) SLC22A6LMNATSHRNFKB1PMP22
Glutarate SCHEMBL7414 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025067483-A1 AMIDE COMPOUNDS 中国药科大学 2025-04-03 WO disclosed
WO-2020156445-A1 HEXONE GLUCOKINASE INHIBITOR AND USE THEREOF 山东轩竹医药科技有限公司 2020-08-06 WO disclosed
CN-104684909-A Tetrazolinone compounds and their use as pesticides SUMITOMO CHEMICAL CO 2015-06-03 CN disclosed
CN-104684908-A Tetrazolinone compounds and their use as pesticides SUMITOMO CHEMICAL CO 2015-06-03 CN disclosed
CN-102036558-A Novel piperidine derivatives as stearoyl-CoA desaturase inhibitors FOREST LAB HOLDINGS LTD 2011-04-27 CN disclosed
CN-101765430-A Novel pyrazole derivatives HOFFMANN LA ROCHE 2010-06-30 CN disclosed
CN-1771235-B Isoxazole compounds VERNALIS CAMBRIDGE LTD 2010-04-28 CN disclosed
CN-1771235-A Isoxazole compounds VERNALIS CAMBRIDGE LTD (GB) 2006-05-10 CN disclosed
CN-1420882-A Substd. oxoazaheterocyclyl compounds AVENTIS PHARM PROD INC (US) 2003-05-28 CN disclosed