⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26797744 | 0.64 | ALDH1A1 (0.32) | — | |
| SCHEMBL2293575 | 0.64 | LMNA (0.34) | — | |
| SCHEMBL11764533 | 0.61 | — | — | |
| SCHEMBL6828416 | 0.60 | BACE1 (0.43) | — | |
| SCHEMBL2230292 | 0.60 | MAPT (0.40) | — | |
| Hydrochloric Acid SCHEMBL8504449 | 0.58 | BACE1 (0.42) | — | |
| SCHEMBL4074635 | 0.58 | MAPT (0.39) | — | |
| Hydrochloric Acid SCHEMBL8502705 | 0.58 | BACE1 (0.42) | — | |
| SCHEMBL14094063 | 0.55 | CACNB4 (0.40) | — | |
| SCHEMBL24479614 | 0.53 | TDP1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263642-A1 | METHODS FOR TREATMENT OF MULTIPLE SCLEROSIS | FIBROGEN, INC. (US) | 2011-10-27 | — | — | US | disclosed |
| EP-2341904-A1 | METHODS FOR TREATMENT OF MULTIPLE SCLEROSIS | Fibrogen, Inc. (US) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010024908-A1 | METHODS FOR TREATMENT OF MULTIPLE SCLEROSIS | FIBROGEN, INC. (US) | 2010-03-04 | — | — | WO | disclosed |