Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GLB1 | P16278 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.34 |
| ▸ | TLR4 | O00206 | 1/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | ARG1 | P05089 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24564842 | 0.92 | DRD3 (0.47) | CYP1A2DRD3SLC6A3GNAO1GNAI3 | |
| SCHEMBL14079710 | 0.87 | CHRNA7 (0.36) | DRD3SLC6A3ARG1 | |
| SCHEMBL13560157 | 0.87 | CHRNA7 (0.36) | DRD3SLC6A3ARG1 | |
| SCHEMBL23710744 | 0.87 | CHRNA7 (0.36) | DRD3SLC6A3ARG1 | |
| SCHEMBL5637780 | 0.82 | SIGMAR1 (0.36) | DRD3SLC6A3ARG1 | |
| SCHEMBL3719924 | 0.82 | DRD3 (0.39) | DRD3SLC6A3ARG1 | |
| SCHEMBL14232939 | 0.81 | CYP1A2 (0.41) | CYP1A2LMNAMAPK1HTTGLB1 | |
| SCHEMBL25817314 | 0.78 | — | — | |
| SCHEMBL10489369 | 0.78 | — | — | |
| SCHEMBL12947991 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020159587-A1 | STRUCTURALLY MODIFIED OPIOIDS FOR PREVENTION AND TREATMENT OF DISEASES AND CONDITIONS | UNIVERSITY OF PADOVA (IT) | 2020-08-06 | — | — | WO | disclosed |