Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ARG1 | P05089 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13652271 | 0.88 | ARG1 (0.36) | DRD3SLC6A3ARG1 | |
| SCHEMBL3913369 | 0.88 | ARG1 (0.36) | DRD3SLC6A3ARG1 | |
| SCHEMBL5962257 | 0.82 | ARG1 (0.30) | ARG1 | |
| SCHEMBL22312944 | 0.82 | CYP1A2 (0.45) | DRD3SLC6A3ARG1 | |
| SCHEMBL5962272 | 0.82 | ARG1 (0.30) | ARG1 | |
| SCHEMBL5637780 | 0.80 | SIGMAR1 (0.36) | DRD3SLC6A3ARG1 | |
| SCHEMBL31331050 | 0.79 | — | — | |
| SCHEMBL31330779 | 0.79 | — | — | |
| SCHEMBL17063292 | 0.79 | — | — | |
| SCHEMBL24564842 | 0.78 | DRD3 (0.47) | DRD3SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138589-A1 | BICYCLIC PYRIMIDINE PI3K INHIBITOR COMPOUNDS SELECTIVE FOR P110 DELTA, AND METHODS OF USE | GENENTECH, INC. (US) | 2010-12-02 | — | — | WO | disclosed |