Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 18/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1980001 | 0.91 | S1PR1 (0.44) | S1PR1S1PR3LMNAKDM4EALDH1A1 | |
| SCHEMBL1981126 | 0.87 | S1PR1 (0.50) | S1PR1S1PR3LMNAKDM4EALDH1A1 | |
| SCHEMBL12522034 | 0.86 | S1PR1 (0.53) | S1PR1S1PR3LMNAS1PR4S1PR5 | |
| SCHEMBL2230853 | 0.83 | S1PR1 (0.49) | S1PR1S1PR3LMNAKDM4EALDH1A1 | |
| SCHEMBL1980482 | 0.83 | S1PR1 (0.52) | S1PR1S1PR3LMNAKDM4EALDH1A1 | |
| SCHEMBL1979878 | 0.83 | S1PR1 (0.49) | S1PR1S1PR3LMNAKDM4EALDH1A1 | |
| SCHEMBL1489283 | 0.81 | S1PR1 (0.68) | S1PR1S1PR3KDM4EALDH1A1HPGD | |
| SCHEMBL1979556 | 0.80 | S1PR1 (0.50) | S1PR1S1PR3LMNAS1PR4S1PR5 | |
| SCHEMBL1981614 | 0.79 | S1PR1 (0.45) | S1PR1S1PR3KDM4ES1PR4S1PR5 | |
| SCHEMBL1980782 | 0.79 | S1PR1 (0.51) | S1PR1S1PR3S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343287-A1 | New 2-aminothiadiazole derivatives | Almirall, S.A. (ES) | 2011-07-13 | — | — | EP | disclosed |
| WO-2011069647-A1 | NEW 2-AMINOTHIADIAZOLE DERIVATIVES | ALMIRALL, S.A. (ES) | 2011-06-16 | — | — | WO | disclosed |