Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 14/20 | 0.58 |
| ▸ | MAPT | P10636 | 12/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 11/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 9/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | HTT | P42858 | 7/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 11/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | MMP14 | P50281 | 1/20 | 0.55 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10085310 | 0.86 | KDM4E (0.53) | KMT2AMAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL19651990 | 0.73 | KAT8 (0.55) | KMT2AMAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL13678890 | 0.72 | KDM4E (0.68) | KMT2AMAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL14518012 | 0.72 | KDM4E (0.68) | KMT2AMAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL26458957 | 0.71 | KMT2A (1.00) | KMT2AMAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL6952167 | 0.69 | KDM4E (0.68) | KMT2AMAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL6952163 | 0.69 | KDM4E (0.68) | KMT2AMAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL28967916 | 0.68 | KMT2A (0.81) | KMT2AMAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL28476008 | 0.68 | KMT2A (0.81) | KMT2AMAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL10035997 | 0.68 | KMT2A (0.81) | KMT2AMAPTMAPK1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230330066-A1 | Vasodilator and Use Thereof | BIORADICAL RESEARCH INSTITUTE CORP. (JP) | 2023-10-19 | — | — | US | disclosed |
| US-20230330066-A1 | Vasodilator and Use Thereof | BIORADICAL RESEARCH INSTITUTE CORP. (JP) | 2023-10-19 | — | — | US | disclosed |
| WO-2021125345-A1 | VASODILATOR AND USE THEREOF | 株式会社バイオラジカル研究所 | 2021-06-24 | — | — | WO | disclosed |
| WO-2020158225-A1 | ANTIOXIDANT AND USE THEREOF | 株式会社バイオラジカル研究所 | 2020-08-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230330066-A1 | Vasodilator and Use Thereof | NOX4, NOX1, NOX5 | KMT2A 3570/4885MAPT 4197/4885MAPK1 133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.