Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PGK1 | P00558 | 1/20 | 0.41 |
| ▸ | PGK2 | P07205 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ESRRG | P62508 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | RXRB | P28702 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25782641 | 0.86 | NPSR1 (0.47) | NR1H4NPSR1PGK1PGK2TSHR | |
| SCHEMBL19052281 | 0.81 | TSHR (0.54) | NPSR1TSHRMEN1KMT2AGAA | |
| SCHEMBL15698253 | 0.78 | NPSR1 (0.45) | NPSR1PGK1PGK2TSHRMEN1 | |
| SCHEMBL22782575 | 0.75 | ESR1 (0.55) | TSHRMEN1KMT2AGAALMNA | |
| SCHEMBL17994314 | 0.74 | LMNA (0.41) | NPSR1TSHRMEN1KMT2AGAA | |
| SCHEMBL26077627 | 0.74 | RXRA (0.43) | NPSR1LMNARXRARXRBPTPN1 | |
| SCHEMBL17994301 | 0.74 | LMNA (0.50) | NPSR1TSHRMEN1KMT2AGAA | |
| SCHEMBL31212638 | 0.74 | LMNA (0.50) | NPSR1TSHRMEN1KMT2AGAA | |
| SCHEMBL17806499 | 0.73 | RXRA (0.58) | EPHX2RXRARXRBPTPN1PTPN5 | |
| SCHEMBL18118552 | 0.73 | PTPN1 (0.41) | NPSR1TSHRMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020159837-A1 | SYNTHESIS STRATEGY FOR GAP PROTECTING GROUP | GAP PEPTIDES LLC (US) | 2020-08-06 | — | — | WO | disclosed |