Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22314699 | 0.86 | MRGPRX4 (0.58) | MRGPRX4KCNH2NPC1RAB9AMEN1 | |
| SCHEMBL22315216 | 0.77 | KCNH2 (0.66) | MRGPRX4KCNH2NPC1RAB9ALMNA | |
| SCHEMBL22315217 | 0.75 | MRGPRX4 (0.52) | MRGPRX4KCNH2FFAR1CYP1A2 | |
| SCHEMBL22315218 | 0.74 | NPC1 (0.49) | MRGPRX4KCNH2PPARGNPC1RAB9A | |
| SCHEMBL22314702 | 0.73 | MRGPRX4 (0.45) | MRGPRX4KCNH2PPARGNPC1RAB9A | |
| SCHEMBL4569966 | 0.73 | KCNH2 (0.75) | MRGPRX4KCNH2NPC1RAB9ALMNA | |
| SCHEMBL958339 | 0.72 | MEN1 (0.51) | HTTL3MBTL1MEN1KMT2ASCN9A | |
| SCHEMBL22315227 | 0.72 | PPARG (0.47) | MRGPRX4KCNH2PPARGLMNAMAPK1 | |
| SCHEMBL9657369 | 0.71 | MRGPRX4 (0.56) | MRGPRX4L3MBTL1KCNH2NPC1RAB9A | |
| SCHEMBL22315231 | 0.70 | L3MBTL1 (0.39) | HTTL3MBTL1PPARGNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111518022-A | Aromatic (hetero) cyclic ether compound with insecticidal activity and preparation method and application thereof | 华东理工大学 | 2020-08-11 | — | — | CN | disclosed |
| WO-2020156512-A1 | AROMATIC (HETERO)CYCLIC ETHER COMPOUND HAVING INSECTICIDAL ACTIVITY, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 华东理工大学 | 2020-08-06 | — | — | WO | disclosed |