SCHEMBL26652153

SCHEMBL26652153

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nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FGF1 P05230 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10310995 1.00 FGF1 (0.33) FGF1
SCHEMBL13222901 1.00 FGF1 (0.33) FGF1
SCHEMBL12253802 1.00 FGF1 (0.33) FGF1
SCHEMBL10001262 1.00 FGF1 (0.33) FGF1
SCHEMBL14622977 0.87 — —
SCHEMBL14624334 0.85 — —
SCHEMBL18098021 0.85 — —
SCHEMBL21123603 0.85 — —
SCHEMBL22317546 0.85 — —
SCHEMBL14537126 0.85 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11801311-B2 Inhibiting or downregulating glycogen synthase by creating premature stop codons using antisense oligonucleotides GENZYME CORPORATION (US) 2023-10-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11801311-B2 Inhibiting or downregulating glycogen synthase by creating premature stop codons using antisense oligonucleotides GYS1, PYGM, TNNC1 FGF1 4720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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