SCHEMBL2231759

SCHEMBL2231759

C=C(C)C(=O)OC(C)CCOc1ccc(C2(c3ccc(OCCC(C)OC(=O)C(=C)C)c(C)c3)c3ccccc3-c3ccccc32)cc1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.42
ESR2 Q92731 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
PDK2 Q15119 1/20 0.32
GAA P10253 1/20 0.32
TDP1 Q9NUW8 2/20 0.32
CHRM5 P08912 1/20 0.31
PPARG P37231 4/20 0.31
PPARD Q03181 4/20 0.31
PPARA Q07869 3/20 0.31
MCHR1 Q99705 1/20 0.31
HTT P42858 2/20 0.31
MAPT P10636 2/20 0.30
TP53 P04637 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2234164 0.90 ESR1 (0.43) ESR1ESR2L3MBTL1ALDH1A1HPGD
SCHEMBL2296138 0.88 KDM4E (0.37) L3MBTL1ALDH1A1PPARGPPARDPPARA
SCHEMBL2399653 0.88 ESR1 (0.38) ESR1ESR2PDK2MEN1KMT2A
SCHEMBL2234920 0.86 ESR1 (0.42) ESR1ESR2L3MBTL1ALDH1A1HPGD
SCHEMBL2231834 0.84 ESR1 (0.46) ESR1ESR2L3MBTL1ALDH1A1HPGD
SCHEMBL2230357 0.84 PDK2 (0.39) MAPK1PDK2TDP1CHRM5HTT
SCHEMBL2234170 0.83 ESR1 (0.45) ESR1ESR2L3MBTL1ALDH1A1HPGD
SCHEMBL4953005 0.81 ESR1 (0.47) ESR1ESR2L3MBTL1ALDH1A1HPGD
SCHEMBL19563140 0.81 ESR1 (0.39) ESR1ESR2L3MBTL1HPGDTSHR
SCHEMBL4956470 0.81 ESR1 (0.35) ESR1ESR2ALDH1A1PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2360194-B1 SILOXANE RESIN COMPOSITION AND PROTECTIVE FILM FOR TOUCH PANEL USING SAME TORAY INDUSTRIES (JP) 2015-03-11 EP disclosed
US-8492450-B2 Siloxane resin composition and protective film for touch panel using the same TORAY INDUSTRIES, INC. (JP) 2013-07-23 US disclosed
US-20110230584-A1 SILOXANE RESIN COMPOSITION AND PROTECTIVE FILM FOR TOUCH PANEL USING THE SAME TORAY INDUSTRIES, INC. (JP) 2011-09-22 US disclosed
EP-2360194-A1 SILOXANE RESIN COMPOSITION AND PROTECTIVE FILM FOR TOUCH PANEL USING SAME Toray Industries, Inc. (JP) 2011-08-24 EP disclosed