SCHEMBL2230357

SCHEMBL2230357

C=C(C)C(=O)OC(C)CCOc1ccc(C2(c3ccc(OCCC(C)OC(=O)C(=C)C)cc3)c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 9/20 0.39
POLB P06746 2/20 0.36
APEX1 P27695 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MAPK1 P28482 1/20 0.35
MEN1 O00255 2/20 0.34
MAPT P10636 2/20 0.34
KMT2A Q03164 2/20 0.34
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
OPRK1 P41145 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
EPHX2 P34913 1/20 0.34
CHRM5 P08912 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL534806 0.89 PDK2 (0.39) PDK2POLBAPEX1HTTTDP1
SCHEMBL28627397 0.88 POLB (0.36) PDK2POLBAPEX1HTTTDP1
SCHEMBL534651 0.87 POLB (0.36) PDK2POLBAPEX1HTTTDP1
SCHEMBL2231393 0.84 THRB (0.40) PDK2POLBMAPK1MEN1MAPT
SCHEMBL2231759 0.84 ESR1 (0.42) PDK2HTTTDP1MAPK1MEN1
SCHEMBL2399653 0.84 ESR1 (0.38) PDK2MEN1KMT2A
SCHEMBL2296138 0.83 KDM4E (0.37) MEN1KMT2AKDM4ELMNASMN1; SMN2
SCHEMBL30800968 0.82 POLB (0.48) PDK2POLBAPEX1HTTTDP1
SCHEMBL157502 0.82 POLB (0.48) PDK2POLBAPEX1HTTTDP1
SCHEMBL534807 0.81 POLB (0.53) PDK2POLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2360194-B1 SILOXANE RESIN COMPOSITION AND PROTECTIVE FILM FOR TOUCH PANEL USING SAME TORAY INDUSTRIES (JP) 2015-03-11 EP disclosed
US-8492450-B2 Siloxane resin composition and protective film for touch panel using the same TORAY INDUSTRIES, INC. (JP) 2013-07-23 US disclosed
US-20110230584-A1 SILOXANE RESIN COMPOSITION AND PROTECTIVE FILM FOR TOUCH PANEL USING THE SAME TORAY INDUSTRIES, INC. (JP) 2011-09-22 US disclosed
EP-2360194-A1 SILOXANE RESIN COMPOSITION AND PROTECTIVE FILM FOR TOUCH PANEL USING SAME Toray Industries, Inc. (JP) 2011-08-24 EP disclosed