SCHEMBL2296138

SCHEMBL2296138

C=C(C)C(=O)OC(C)CCOc1ccc(C2(c3ccc(OCCC(C)OC(=O)C(=C)C)c(-c4ccccc4)c3)c3ccccc3-c3ccccc32)cc1-c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.37
ALDH1A1 P00352 5/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
SLC6A9 P48067 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
PKM P14618 1/20 0.36
PTGDR2 Q9Y5Y4 3/20 0.35
LMNA P02545 1/20 0.35
PPARG P37231 1/20 0.35
PPARD Q03181 1/20 0.35
PPARA Q07869 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
THRA P10827 1/20 0.35
THRB P10828 1/20 0.35
ADRB2 P07550 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2231416 0.90 PTGDR2 (0.37) KDM4EALDH1A1SMN1; SMN2SLC6A9MEN1
SCHEMBL2231759 0.88 ESR1 (0.42) KDM4EALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL2231170 0.86 KDM4E (0.37) KDM4EALDH1A1SMN1; SMN2SLC6A9MEN1
SCHEMBL29499715 0.85 KDM4E (0.40) KDM4EALDH1A1SMN1; SMN2SLC6A9MEN1
SCHEMBL29499719 0.85 KDM4E (0.40) KDM4EALDH1A1SMN1; SMN2SLC6A9MEN1
SCHEMBL2230816 0.85 KDM4E (0.40) KDM4EALDH1A1SMN1; SMN2SLC6A9MEN1
SCHEMBL2231419 0.84 KDM4E (0.40) KDM4EALDH1A1SMN1; SMN2SLC6A9MEN1
SCHEMBL2230357 0.83 PDK2 (0.39) KDM4ESMN1; SMN2MEN1KMT2ALMNA
SCHEMBL2399653 0.80 ESR1 (0.38) MEN1KMT2A
SCHEMBL4956470 0.79 ESR1 (0.35) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2360194-B1 SILOXANE RESIN COMPOSITION AND PROTECTIVE FILM FOR TOUCH PANEL USING SAME TORAY INDUSTRIES (JP) 2015-03-11 EP disclosed
US-8492450-B2 Siloxane resin composition and protective film for touch panel using the same TORAY INDUSTRIES, INC. (JP) 2013-07-23 US disclosed
US-20110230584-A1 SILOXANE RESIN COMPOSITION AND PROTECTIVE FILM FOR TOUCH PANEL USING THE SAME TORAY INDUSTRIES, INC. (JP) 2011-09-22 US disclosed
EP-2360194-A1 SILOXANE RESIN COMPOSITION AND PROTECTIVE FILM FOR TOUCH PANEL USING SAME Toray Industries, Inc. (JP) 2011-08-24 EP disclosed