SCHEMBL2231797

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Hydrochloric Acid SCHEMBL2235571	0.92	TSHR (0.56)	TSHRKDM4ERAB9ANPC1ALDH1A1
	SCHEMBL1780598	0.91	KDM4E (0.61)	TSHRKDM4EMEN1KMT2AHRH3
	SCHEMBL2231546	0.89	TSHR (0.62)	TSHRRAB9ANPC1ALDH1A1MEN1
	SCHEMBL2236728	0.89	SIGMAR1 (0.54)	TSHRLTA4HHRH3SIGMAR1SMN1; SMN2
	SCHEMBL2294267	0.89	SIGMAR1 (0.54)	TSHRLTA4HHRH3SIGMAR1SMN1; SMN2
	SCHEMBL2232165	0.89	CXCR4 (0.59)	TSHRRAB9ANPC1ALDH1A1MEN1
	SCHEMBL2231787	0.89	CXCR4 (0.59)	TSHRRAB9ANPC1ALDH1A1MEN1
	Hydrochloric Acid SCHEMBL2232210	0.89	CHRM3 (0.50)	TSHRKDM4EALDH1A1MEN1KMT2A
	Hydrochloric Acid SCHEMBL2233324	0.88	CXCR4 (0.58)	TSHRMEN1KMT2ALTA4HHRH3
	SCHEMBL2231202	0.87	DRD2 (0.53)	TSHRMEN1KMT2ALTA4HHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.