SCHEMBL22318

SCHEMBL22318

Cc1[c]cc(Cl)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL509338 0.80 CYP1A2 (0.42)
SCHEMBL8683649 0.75 MAOA (0.47)
SCHEMBL22594 0.71
SCHEMBL7101528 0.71
SCHEMBL38194 0.71
SCHEMBL596190 0.69
SCHEMBL513430 0.68 ESR2 (0.51)
SCHEMBL19917 0.67
SCHEMBL359149 0.67
SCHEMBL359463 0.67 GAA (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1640 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4396348-A2 HIGH MOLECULAR WEIGHT MODIFIED DSRNA COMPOSITIONS Nanosur LLC (US) 2024-07-10 EP claimed
CN-118302524-A High molecular weight modified dsRNA compositions 纳诺索尔公司 2024-07-05 CN claimed
CN-118290298-A Benzoyl hydrazine compound and synthetic method and application thereof 南京农业大学 2024-07-05 CN claimed
US-20240174603-A1 MODULATORS OF PROTEIN PHOSPHATASE 2A (PP2A) AND METHODS USING SAME RAPPTA THERAPEUTICS OY (FI) 2024-05-30 US claimed
US-11987588-B2 Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure and disorders related thereto ARENA PHARMACEUTICALS, INC. (US) 2024-05-21 US claimed
US-20240002344-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION FIBROGEN, INC. 2024-01-04 US claimed
EP-4288412-A1 MODULATORS OF PROTEIN PHOSPHATASE 2A (PP2A) AND METHODS USING SAME Rappta Therapeutics Oy (FI) 2023-12-13 EP claimed
EP-4204400-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION Fibrogen, Inc. (US) 2023-07-05 EP claimed
CN-116348450-A Compounds, compositions and methods for histone lysine demethylase inhibition 菲布罗根有限公司 2023-06-27 CN claimed
WO-2023113114-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING OVERACTIVE BLADDER 광주과학기술원 2023-06-22 WO claimed
EP-0007184-B1 UREA DERIVATIVES, PROCESSES FOR PREPARING THEM AND COMPOSITIONS CONTAINING THEM AMERICAN HOME PRODUCTS CORPORATION (US) 1982-06-30 EP claimed
US-4336325-A CONTAING A MAGENTA COLOR-FORMING COUPLER WHICH PREVENTS YELLOW STAIN FUJI PHOTO FILM CO., LTD. (JP) 1982-06-22 US claimed
US-4297373-A CARDIOVASCULAR DISORDERS; ANTIARRHYTHMIA AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1981-10-27 US claimed
US-4262851-A HIGH SPEED MILLING WITHOUT SURFACTANTS BASF AKTIENGESELLSCHAFT (DE) 1981-04-21 US claimed
US-4224242-A ANTI-ARRHYTHMIC AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1980-09-23 US claimed
WO-1980000151-A1 N-(3-ALKYLAMINOPROPYL)-N'-PHENYLUREAS AMERICAN HOME PROD (US) 1980-02-07 WO claimed
EP-0007184-A1 Urea derivatives, processes for preparing them and compositions containing them AMERICAN HOME PRODUCTS CORPORATION (US) 1980-01-23 EP claimed
US-4163670-A PYRAZOLONE COUPLERS FUJI PHOTO FILM CO., LTD. (JP) 1979-08-07 US claimed
US-4159983-A Pure and substantially pure asymmetric 1:2 cobalt complexes of monoazo compounds SANDOZ LTD. (CH) 1979-07-03 US claimed
US-3983116-A Herbicidal triazines E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-09-28 US claimed