Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7764 | 0.83 | CA1 (0.53) | HTR2ACA1CA2FABP5TSHR | |
| SCHEMBL28678862 | 0.81 | CA1 (0.40) | HTR2ACA1CA2FABP5HRH3 | |
| SCHEMBL18055683 | 0.80 | CA1 (0.42) | HTR2ACA1CA2GPR3FABP5 | |
| SCHEMBL9449380 | 0.78 | HRH3 (0.55) | HTR2AGAAGPR3HRH3MTNR1A | |
| SCHEMBL3056225 | 0.77 | TTR (0.42) | CA1CA2GAAFABP5KDM4E | |
| SCHEMBL135438 | 0.76 | CA1 (0.44) | HTR2ACA1CA2FABP5HRH3 | |
| SCHEMBL3331520 | 0.76 | PTPRC (0.42) | CA1CA2GAAGPR3CYP19A1 | |
| Dimethylformamide SCHEMBL28310394 | 0.75 | CA1 (0.43) | HTR2ACA1CA2GPR3FABP5 | |
| SCHEMBL1934963 | 0.75 | AKR1B1 (0.41) | CA1CA2GAAFABP5TSHR | |
| Hydrochloric Acid SCHEMBL8638272 | 0.74 | HTR2A (0.48) | HTR2AGAAGPR3HRH3HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3924369-A1 | LONG-ACTING GLP-2 ANALOGS | OPKO Biologics Ltd. (IL) | 2021-12-22 | — | — | EP | claimed |
| CN-113710692-A | Long-acting GLP-2 analogs | OPKO生物科学有限公司 | 2021-11-26 | — | — | CN | claimed |
| WO-2020165900-A1 | LONG-ACTING GLP-2 ANALOGS | OPKO BIOLOGICS LTD. (IL) | 2020-08-20 | — | — | WO | claimed |
| US-20200254065-A1 | LONG-ACTING GLP-2 ANALOGS | OPKO BIOLOGICS LTD. (IL) | 2020-08-13 | — | — | US | claimed |
| EP-3924369-A1 | LONG-ACTING GLP-2 ANALOGS | OPKO Biologics Ltd. (IL) | 2021-12-22 | — | — | EP | disclosed |
| CN-113710692-A | Long-acting GLP-2 analogs | OPKO生物科学有限公司 | 2021-11-26 | — | — | CN | disclosed |
| WO-2020165900-A1 | LONG-ACTING GLP-2 ANALOGS | OPKO BIOLOGICS LTD. (IL) | 2020-08-20 | — | — | WO | disclosed |
| US-20200254065-A1 | LONG-ACTING GLP-2 ANALOGS | OPKO BIOLOGICS LTD. (IL) | 2020-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200254065-A1 | LONG-ACTING GLP-2 ANALOGS | GLP1R, GIPR, GCGR | HTR2A 342/4885CA1 4827/4885CA2 4454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.