Dimethylformamide

Dimethylformamide

SCHEMBL28310394

CN(C)C=O.O=[C]OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
GPR3 P46089 1/20 0.37
HTR2A P28223 1/20 0.37
KMT2A Q03164 3/20 0.36
FABP5 Q01469 3/20 0.35
FABP7 O15540 2/20 0.35
SLC22A2 O15244 1/20 0.34
SLC22A3 O75751 1/20 0.34
EPHX2 P34913 1/20 0.34
CASP3 P42574 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7764 0.87 CA1 (0.53) CA1CA2HTR2AKMT2AFABP5
SCHEMBL28101345 0.83 CA1 (0.44) CA1CA2HTR2AKMT2AFABP5
Tert-Butyl Formate SCHEMBL2890845 0.82 CA1 (0.41) CA1CA2HTR2AKMT2AFABP5
Dimethylformamide SCHEMBL28264885 0.81 CA1 (0.45) CA1CA2GPR3HTR2AKMT2A
SCHEMBL28310443 0.77 CA1 (0.44) CA1CA2HTR2AKMT2AFABP5
SCHEMBL27768296 0.77 CA1 (0.41) CA1CA2HTR2AKMT2AFABP5
SCHEMBL22320252 0.75 HTR2A (0.40) CA1CA2GPR3HTR2AFABP5
SCHEMBL18055683 0.75 CA1 (0.42) CA1CA2GPR3HTR2AKMT2A
SCHEMBL28678862 0.72 CA1 (0.40) CA1CA2HTR2AKMT2AFABP5
SCHEMBL29479940 0.72 KMT2A (0.47) CA1CA2KMT2AFABP5FABP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110093408-A A kind of DNA encoding compound library and method for screening compound 成都先导药物开发股份有限公司 2019-08-06 CN disclosed