SCHEMBL223204

SCHEMBL223204

CC(=O)c1ccc(SSc2ccc(C(C)=O)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.73
LMNA P02545 2/20 0.73
L3MBTL1 Q9Y468 2/20 0.73
ALDH1A1 P00352 1/20 0.61
MAPT P10636 6/20 0.52
RAB9A P51151 5/20 0.52
KMT2A Q03164 3/20 0.52
SMN1; SMN2 Q16637 4/20 0.50
HSD17B1 P14061 1/20 0.50
NPC1 O15118 4/20 0.47
TAAR1 Q96RJ0 1/20 0.47
MAPK1 P28482 2/20 0.46
NOS3 P29474 2/20 0.46
NOS1 P29475 2/20 0.46
MEN1 O00255 1/20 0.45
HTT P42858 1/20 0.45
NLRP1 Q9C000 1/20 0.45
STAT3 P40763 1/20 0.45
STAT1 P42224 1/20 0.45
TDP1 Q9NUW8 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28522448 0.87 HPGD (0.57) HPGDLMNAL3MBTL1ALDH1A1MAPT
SCHEMBL835108 0.84 HPGD (1.00) HPGDLMNAL3MBTL1ALDH1A1MAPT
SCHEMBL1755726 0.84 HPGD (1.00) HPGDLMNAL3MBTL1ALDH1A1MAPT
Acetophenone SCHEMBL28222172 0.83 HPGD (0.67) HPGDLMNAL3MBTL1ALDH1A1MAPT
SCHEMBL50646 0.83 MAPT (0.68) HPGDLMNAL3MBTL1ALDH1A1MAPT
SCHEMBL195321 0.82 HPGD (0.70) HPGDLMNAL3MBTL1ALDH1A1MAPT
SCHEMBL13346835 0.82 HPGD (0.70) HPGDLMNAL3MBTL1ALDH1A1MAPT
SCHEMBL27475366 0.80 MAPT (0.59) HPGDLMNAL3MBTL1ALDH1A1MAPT
SCHEMBL18735663 0.80 HPGD (0.67) HPGDLMNAL3MBTL1ALDH1A1MAPT
SCHEMBL27700625 0.80 HPGD (0.67) HPGDLMNAL3MBTL1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 671 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6998444-B2 Vulcanization accelerator in crosslinked cis-polybutadiene core for increase compression and low coefficient of restitution, without causing any isomerism; use small amounts of crosslinker zinc diacrylate ACUSHNET COMPANY (US) 2006-02-14 US claimed
US-20050256274-A1 Golf ball core compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-11-17 US claimed
US-6960629-B2 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions ACUSHNET COMPANY (US) 2005-11-01 US claimed
US-20040230006-A1 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-18 US claimed
US-20040230005-A1 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions ACUSHNET COMPANY 2004-11-18 US claimed
WO-2023001999-A1 C2-THIOETHER TRYPTOPHAN TRIMERS AND TETRAMERS FOR THE TREATMENT OF BETACORONOAVIRUS INFECTIONS 1. CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) 2023-01-26 WO disclosed
EP-3292893-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-2656882-B1 Golf ball SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
US-10933285-B2 Multi-layer core golf ball ACUSHNET COMPANY (US) 2021-03-02 US disclosed
EP-3156441-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-25 EP disclosed
EP-3329971-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-18 EP disclosed
EP-2666521-B1 Golf ball SUMITOMO RUBBER IND (JP) 2020-09-02 EP disclosed
US-20020006837-A1 Wound golf ball having cast polyurethane cover ACUSHNET COMPANY 2002-01-17 US disclosed
WO-2000038794-A9 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING AN ORGANOSULFUR CATALYST AND METHOD FOR MAKING SAME ACUSHNET CO (US) 2001-11-01 WO disclosed
US-20010024982-A1 Thin-layer-covered multilayer golf ball JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2001-09-27 US disclosed
US-6291592-B1 HARDNESS, STIFFNESS ACUSHNET COMPANY 2001-09-18 US disclosed
WO-2000038794-A1 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING AN ORGANOSULFUR CATALYST AND METHOD FOR MAKING SAME ACUSHNET COMPANY (US) 2000-07-06 WO disclosed
WO-2000038793-A1 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING ELEMENTAL CATALYST AND METHOD FOR MAKING SAME ACUSHNET COMPANY (US) 2000-07-06 WO disclosed
WO-2000038795-A1 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING AROMATIC CATALYST AND METHOD FOR MAKING SAME ACUSHNET COMPANY (US) 2000-07-06 WO disclosed
US-5861465-A VULCANIZED RUBBER CONTAINING A DIPHENYL AND DINAPHTHYL DISULFIDE; IMPACT STRENGTH, RESILIENCE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 1999-01-19 US disclosed