Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | KIF11 | P52732 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoproturon SCHEMBL8518619 | 0.95 | TSHR (0.67) | TSHRKIF11CA12CA1CA2 | |
| Isoproturon SCHEMBL62200 | 0.95 | TSHR (0.67) | TSHRKIF11CA12CA1CA2 | |
| Isoproturon SCHEMBL28224193 | 0.93 | TSHR (0.65) | TSHRKIF11CA12CA1CA2 | |
| Isoproturon SCHEMBL27446851 | 0.87 | TSHR (0.50) | TSHRKIF11CA12CA1CA2 | |
| Isoproturon SCHEMBL29899137 | 0.85 | TSHR (0.54) | TSHRKIF11CA12CA1CA2 | |
| Isoproturon SCHEMBL11209065 | 0.85 | TSHR (0.51) | TSHRKIF11CA12CA1CA2 | |
| Isoproturon SCHEMBL7202232 | 0.83 | APEX1 (0.79) | TSHRCA2CA9APEX1SMN1; SMN2 | |
| Isoproturon SCHEMBL28241261 | 0.83 | NPY5R (0.60) | TSHRRAB9A | |
| Isoproturon SCHEMBL28366631 | 0.82 | TSHR (0.51) | TSHRALDH1A1HPGDRAB9A | |
| SCHEMBL687878 | 0.81 | TSHR (0.79) | TSHRCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2529028-A1 | POLYNUCLEOTIDE AND POLYPEPTIDE SEQUENCES ASSOCIATED WITH HERBICIDE TOLERANCE | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 2012-12-05 | — | — | EP | disclosed |
| EP-2529027-A1 | HPPD-INHIBITOR HERBICIDE TOLERANCE | Pioneer-Hi-Bred International, Inc. (US) | 2012-12-05 | — | — | EP | disclosed |
| WO-2011094199-A1 | POLYNUCLEOTIDE AND POLYPEPTIDE SEQUENCES ASSOCIATED WITH HERBICIDE TOLERANCE | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 2011-08-04 | — | — | WO | disclosed |
| WO-2011094205-A1 | HPPD-INHIBITOR HERBICIDE TOLERANCE | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 2011-08-04 | — | — | WO | disclosed |