Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.70 |
| ▸ | CA1 | P00915 | 6/20 | 0.70 |
| ▸ | CA2 | P00918 | 6/20 | 0.70 |
| ▸ | CA4 | P22748 | 6/20 | 0.70 |
| ▸ | CA5A | P35218 | 6/20 | 0.70 |
| ▸ | CA7 | P43166 | 6/20 | 0.70 |
| ▸ | CA9 | Q16790 | 6/20 | 0.70 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | LAP3 | P28838 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4193997 | 0.86 | L3MBTL1 (0.69) | CA12CA1CA2CA4CA5A | |
| SCHEMBL7623138 | 0.86 | L3MBTL1 (0.63) | CA12CA1CA2CA4CA5A | |
| SCHEMBL2608782 | 0.84 | L3MBTL1 (0.61) | CA12CA1CA2CA4CA5A | |
| SCHEMBL561190 | 0.82 | L3MBTL1 (1.00) | CA12CA1CA2CA4CA5A | |
| SCHEMBL20704090 | 0.81 | L3MBTL1 (0.62) | CA12CA1CA2CA4CA5A | |
| SCHEMBL9469076 | 0.81 | L3MBTL1 (0.61) | CA12CA1CA2CA4CA5A | |
| SCHEMBL2535071 | 0.79 | L3MBTL1 (0.53) | CA12CA1CA2CA4CA5A | |
| SCHEMBL1028971 | 0.79 | L3MBTL1 (0.53) | CA12CA1CA2CA4CA5A | |
| SCHEMBL976099 | 0.79 | L3MBTL1 (0.76) | CA12CA1CA2CA4CA5A | |
| SCHEMBL407307 | 0.78 | L3MBTL1 (0.61) | CA12CA1CA2CA4CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10927135-B2 | Metal-free direct arylation of dialkyl phosphonates for the synthesis of mixed alkyl aryl phosphonates | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (US) | 2021-02-23 | — | — | US | disclosed |
| US-20200255461-A1 | METAL-FREE DIRECT ARYLATION OF DIALKYL PHOSPHONATES FOR THE SYNTHESIS OF MIXED ALKYL ARYL PHOSPHONATES | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2020-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200255461-A1 | METAL-FREE DIRECT ARYLATION OF DIALKYL PHOSPHONATES FOR THE SYNTHESIS OF MIXED ALKYL ARYL PHOSPHONATES | SLC35B2, PPIP5K2, PPA1 | CA12 3108/4885CA1 2467/4885CA2 1238/4885 |
| US-10927135-B2 | Metal-free direct arylation of dialkyl phosphonates for the synthesis of mixed alkyl aryl phosphonates | SLC35B2, PPIP5K2, PPA1 | CA12 3108/4885CA1 2467/4885CA2 1238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.