Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 18/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11231804 | 0.81 | HRH3 (0.51) | HRH3KCNH2 | |
| SCHEMBL4061767 | 0.77 | CYP2A6 (0.50) | HRH3ALDH1A1 | |
| SCHEMBL11142730 | 0.76 | KMT2A (0.53) | HRH3BRD4KDM4EALDH1A1RAB9A | |
| SCHEMBL15885730 | 0.76 | KMT2A (0.53) | — | |
| SCHEMBL21233325 | 0.75 | PHGDH (0.35) | — | |
| SCHEMBL22951397 | 0.75 | LATS1 (0.37) | ALDH1A1 | |
| SCHEMBL21408757 | 0.73 | ALDH1A1 (0.45) | KDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL3089686 | 0.73 | HRH3 (0.54) | HRH3KCNH2 | |
| SCHEMBL11397967 | 0.73 | HRH3 (0.54) | HRH3BRD4KDM4EALDH1A1RAB9A | |
| SCHEMBL11144982 | 0.73 | HRH3 (0.54) | HRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020161270-A1 | HERBICIDAL PYRIDAZINUM BASED COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-13 | — | — | WO | disclosed |
| WO-2020161270-A1 | HERBICIDAL PYRIDAZINUM BASED COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-13 | — | — | WO | disclosed |