Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 11/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | LATS1 | O95835 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | WNT3A | P56704 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19105638 | 0.81 | GSK3B (0.41) | PHGDHCYP11B1CYP11B2GPR142 | |
| SCHEMBL4547930 | 0.78 | PHGDH (0.49) | PHGDHCYP11B1CYP11B2 | |
| SCHEMBL21927844 | 0.75 | PHGDH (0.42) | PHGDH | |
| SCHEMBL22322303 | 0.75 | HRH3 (0.46) | — | |
| SCHEMBL14263740 | 0.75 | PHGDH (0.46) | PHGDHCYP11B1CYP11B2 | |
| SCHEMBL22951397 | 0.74 | LATS1 (0.37) | PDE10ALATS1 | |
| SCHEMBL11965497 | 0.73 | MAPT (0.45) | PHGDH | |
| SCHEMBL21408757 | 0.73 | ALDH1A1 (0.45) | LATS1 | |
| SCHEMBL11886210 | 0.71 | KMO (0.43) | PHGDH | |
| SCHEMBL15885730 | 0.68 | KMT2A (0.53) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |
| WO-2019148851-A1 | FIVE-MEMBERED RING-SUBSTITUTED PYRIDAZINOL COMPOUND AND DERIVATIVES THEREOF, PREPARATION METHOD, HERBICIDAL COMPOSITION, AND APPLICATION | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |