Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22336356 | 0.98 | ACHE (0.35) | ACHEKDM4ENPSR1 | |
| SCHEMBL22322600 | 0.74 | — | — | |
| Bromide SCHEMBL22322603 | 0.73 | CA2 (0.35) | — | |
| SCHEMBL22322559 | 0.73 | — | — | |
| SCHEMBL22322594 | 0.71 | CA2 (0.37) | — | |
| SCHEMBL22322561 | 0.69 | — | — | |
| SCHEMBL1711802 | 0.68 | HDAC1 (0.37) | ACHEKDM4ENPSR1 | |
| SCHEMBL777146 | 0.66 | ACHE (0.56) | ACHENPSR1 | |
| SCHEMBL5488946 | 0.65 | HPGD (0.52) | ACHEKDM4ENPSR1 | |
| SCHEMBL29449953 | 0.64 | GAA (0.46) | ACHENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020161248-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-13 | — | — | WO | disclosed |