Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | STAMBP | O95630 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 8/20 | 0.37 |
| ▸ | VEGFA | P15692 | 4/20 | 0.37 |
| ▸ | FLT1 | P17948 | 4/20 | 0.37 |
| ▸ | EGLN3 | Q9H6Z9 | 3/20 | 0.37 |
| ▸ | XDH | P47989 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22336173 | 0.91 | KDM4E (0.48) | KDM4EGAASMN1; SMN2MEN1TSHR | |
| Trifluoroacetic Acid SCHEMBL22322615 | 0.89 | KDM4E (0.38) | KDM4EEGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL22322616 | 0.85 | SMN1; SMN2 (0.36) | KDM4EGAASMN1; SMN2MEN1TSHR | |
| SCHEMBL22336362 | 0.77 | KDM4E (0.46) | KDM4ESMN1; SMN2KMT2AEGLN1VEGFA | |
| SCHEMBL22336302 | 0.69 | ALDH1A1 (0.49) | KDM4ETSHRXDHMAPK1ALDH1A1 | |
| SCHEMBL22322608 | 0.69 | USP2 (0.44) | — | |
| SCHEMBL8947242 | 0.68 | KMT2A (0.67) | KDM4EGAASMN1; SMN2MEN1TSHR | |
| Iodide SCHEMBL22322566 | 0.68 | ALDH1A1 (0.47) | KDM4ETSHRXDHMAPK1ALDH1A1 | |
| SCHEMBL22322593 | 0.67 | KDM4E (0.51) | KDM4EGAASMN1; SMN2MEN1TSHR | |
| SCHEMBL22322556 | 0.67 | HPGDS (0.36) | SMN1; SMN2XDHLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020161248-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-13 | — | — | WO | disclosed |