Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANXA2 | P07355 | 14/20 | 0.66 |
| ▸ | S100A10 | P60903 | 14/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2231482 | 0.89 | ANXA2 (0.58) | ANXA2S100A10ALDH1A1CCR1MEN1 | |
| SCHEMBL2232974 | 0.87 | ANXA2 (0.65) | ANXA2S100A10ALDH1A1 | |
| SCHEMBL2236163 | 0.86 | ANXA2 (0.66) | ANXA2S100A10ALDH1A1CCR1MEN1 | |
| SCHEMBL2236328 | 0.85 | ALDH1A1 (0.66) | ANXA2S100A10ALDH1A1MAPTCCR1 | |
| SCHEMBL2235286 | 0.83 | ANXA2 (0.67) | ANXA2S100A10ALDH1A1CCR1MEN1 | |
| SCHEMBL2230926 | 0.81 | ANXA2 (0.66) | ANXA2S100A10ALDH1A1CCR1MEN1 | |
| SCHEMBL2233884 | 0.80 | ANXA2 (0.67) | ANXA2S100A10ALDH1A1CCR1MEN1 | |
| SCHEMBL2233246 | 0.80 | CCR1 (0.59) | ANXA2S100A10ALDH1A1MAPTCCR1 | |
| SCHEMBL2299703 | 0.79 | ANXA2 (0.70) | ANXA2S100A10ALDH1A1CCR1MEN1 | |
| SCHEMBL2234993 | 0.78 | ANXA2 (0.65) | ANXA2S100A10ALDH1A1CCR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092505-A1 | S100 PROTEIN BINDING INTERACTION INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2011-08-04 | — | — | WO | claimed |
| WO-2011092505-A1 | S100 PROTEIN BINDING INTERACTION INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2011-08-04 | — | — | WO | disclosed |