SCHEMBL2232367

SCHEMBL2232367

CO[Si](C)(OC)OCC1CO1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.43
TSHR P16473 5/20 0.40
MAPK1 P28482 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
TDP1 Q9NUW8 3/20 0.36
TP53 P04637 4/20 0.35
CYP3A4 P08684 2/20 0.35
GLA P06280 1/20 0.34
MAPT P10636 2/20 0.32
HPGD P15428 2/20 0.32
HIF1A Q16665 2/20 0.32
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
KMT2A Q03164 1/20 0.32
PPARG P37231 1/20 0.32
PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL647425 0.87 ALDH1A1 (0.48) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL27981682 0.83 TSHR (0.44) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL299427 0.81 ALDH1A1 (0.43) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL18259714 0.81 TSHR (0.44) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL27618829 0.81 TSHR (0.50) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL3177081 0.81 ALDH1A1 (0.48) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL6811986 0.81 ALDH1A1 (0.43) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL5699753 0.79 ALDH1A1 (0.41) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL8622001 0.79 SMN1; SMN2 (0.42) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL19125756 0.78 TSHR (0.64) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114891344-A Antistatic flame-retardant nylon 6 composite material 江苏瑞美福新材料有限公司 2022-08-12 CN claimed
CN-112778754-B Preparation method of antistatic flame-retardant nylon 6 composite material 浙江工业大学 2022-04-05 CN claimed
CN-112778754-A Preparation method of antistatic flame-retardant nylon 6 composite material 浙江工业大学 2021-05-11 CN claimed
CN-1136250-C Crosslinked solid polyelectrolytes and their use ������������ʽ���� 2004-01-28 CN claimed
EP-0620255-B1 Antifogging abrasion resistant coating composition and synthetic resin article coated therewith LUCKY LTD (KR) 2002-02-27 EP claimed
EP-0226934-A2 Curable organosiloxane composition Toray Silicone Co., Ltd. (JP) 1987-07-01 EP claimed
JP-58126501-A None JP disclosed
JP-63099221-A None JP disclosed
CN-116041709-B Preparation method and application of photo-curing phenyl fluorosilicone modified epoxy paint and coating 安徽立兴新材料有限公司 2024-07-16 CN disclosed
CN-117859097-A Method for manufacturing substrate with cured film, and element provided with substrate with cured film 东丽株式会社 2024-04-09 CN disclosed
CN-110573964-B Negative photosensitive resin composition and cured film 东丽株式会社 2023-11-03 CN disclosed
CN-111373325-B Silicone resin composition, cured film, and display device 东丽株式会社 2023-10-17 CN disclosed
CN-116041709-A Preparation method and application of photo-curing phenyl fluorosilicone modified epoxy paint and coating 陕西科技大学 2023-05-02 CN disclosed
EP-0939845-A1 OVENABLE FOOD TRAY AND ITS MANUFACTURING METHOD Stora Enso Oyj (FI) 1999-09-08 EP disclosed
EP-0939848-A1 METHODS FOR MANUFACTURING PACKAGING BOARD Stora Enso Oyj (FI) 1999-09-08 EP disclosed
CN-1215416-A Crss-linked solid polyelectrolyte and use thereof DAISO CO LTD (JP) 1999-04-28 CN disclosed
WO-1998022656-A1 METHODS FOR MANUFACTURING PACKAGING BOARD STORA ENSO OYJ (FI) 1998-05-28 WO disclosed
WO-1998022654-A1 OVENABLE FOOD TRAY AND ITS MANUFACTURING METHOD STORA ENSO OYJ (FI) 1998-05-28 WO disclosed
JP-S6399221-A PRODUCTION OF EPOXY RESIN COMPOSITION FOR SEALING SEMICONDUCTOR SUMITOMO BAKELITE CO LTD 1988-04-30 JP disclosed
JP-S58126501-A SYNTHETIC RESIN LENS SEIKO EPSON CORP 1983-07-28 JP disclosed