SCHEMBL299427

SCHEMBL299427

CO[Si](OC)(OC)OCC1CO1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.43
TSHR P16473 5/20 0.40
MAPK1 P28482 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
TDP1 Q9NUW8 3/20 0.36
TP53 P04637 4/20 0.35
CYP3A4 P08684 2/20 0.35
GLA P06280 1/20 0.34
MAPT P10636 2/20 0.32
HPGD P15428 2/20 0.32
HIF1A Q16665 2/20 0.32
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
KMT2A Q03164 1/20 0.32
PPARG P37231 1/20 0.32
PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclopropane SCHEMBL9353604 0.96 ALDH1A1 (0.40) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL6811986 0.95 ALDH1A1 (0.43) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL3177081 0.95 ALDH1A1 (0.48) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL2783666 0.85 TSHR (0.46) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL2064538 0.81 TSHR (0.52) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL18259714 0.81 TSHR (0.44) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL2232367 0.81 ALDH1A1 (0.43) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL3856312 0.79 SMN1; SMN2 (0.42) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL27721084 0.78 SMN1; SMN2 (0.52) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL305200 0.78 TSHR (0.59) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1002 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4584326-A1 CURABLE POLYMER COMPOSITION HAVING IMPROVED WASH-OFF RESISTANCE Zephyros Inc. (US) 2025-07-16 EP claimed
CN-120060875-A System for synthesizing oligonucleotides, application and method thereof 苏州硅基生物科技有限公司 2025-05-30 CN claimed
CN-119836449-A Curable polymer composition with improved wash-off resistance 泽费罗斯股份有限公司 2025-04-15 CN claimed
CN-118219616-B Aluminum substrate capable of realizing photocuring shaping after bending 东莞市艾赛伦电子有限公司 2024-12-06 CN claimed
CN-110596911-B Color-changing lens and preparation method and application thereof 上海康耐特光学有限公司 2024-10-29 CN claimed
CN-114112911-B Infrared optical fiber evanescent wave sensor for online detection and preparation method 中国地质调查局水文地质环境地质调查中心 2024-07-12 CN claimed
CN-118219616-A Aluminum substrate capable of realizing photocuring shaping after bending 东莞市艾赛伦电子有限公司 2024-06-21 CN claimed
CN-118184691-A Alkylene oxide hydrolysis-resistant stabilizer containing silane structure and preparation method thereof 宁波三邦超细纤维有限公司 2024-06-14 CN claimed
CN-118125719-A Sulfur quantum dot nano mesoporous glass and preparation method thereof 中国科学院上海光学精密机械研究所 2024-06-04 CN claimed
CN-118059687-A High-monovalent permeation selectivity double-side-chain anion exchange membrane and preparation method thereof 浙江工业大学 2024-05-24 CN claimed
EP-1380626-A1 Silane triol capped epoxy-adhesion promotor for adhesive-bonded metal substrates The Boeing Company (US) 2004-01-14 EP claimed
US-20040005455-A1 Silane triol capped epoxy-amine adhesion promoter for adhesive-bonded metal substrates BOEING COMPANY, THE 2004-01-08 US claimed
US-6478886-B1 Agent for sealing metallic ground coats, especially ground coats consisting of zinc or zinc alloys KUNZ GMBH (DE) 2002-11-12 US claimed
EP-1070156-A1 AGENT FOR SEALING METALLIC GROUND COATS, ESPECIALLY GROUND COATS CONSISTING OF ZINC OR ZINC ALLOYS Kunz GmbH (DE) 2001-01-24 EP claimed
WO-1999051793-A1 AGENT FOR SEALING METALLIC GROUND COATS, ESPECIALLY GROUND COATS CONSISTING OF ZINC OR ZINC ALLOYS KUNZ GMBH (DE) 1999-10-14 WO claimed
US-5565518-A OLIGOMER IS ADDITION PRODUCT OF ATLEAST ONE 3-GLYCIDOXYPROPYLALKOXY SILOXANE AND ATLEAST ONE SECONDARY HYDROXYALKYLAMINE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-10-15 US claimed
EP-0394398-A1 NANOPARTICLE WITH BOUND ENZYME AND BOUND LIGAND USEFUL IN ANALYSIS. NILSSON KURT G I (SE) 1990-10-31 EP claimed
WO-1990004181-A1 NANOPARTICLE WITH A BOUND ENZYME AND ANOTHER LIGAND USEFUL IN ANALYSIS NILSSON KURT G I (SE) 1990-04-19 WO claimed
US-4151150-A COUPLING AGENTS FOR IMPROVED STRENGTH AND ADHESION THE DOW CHEMICAL COMPANY (US) 1979-04-24 US claimed
US-4065417-A POLYVINYL ACETATE, ORGANOSILANE COUPLING AGENT OWENS-CORNING FIBERGLAS CORPORATION (US) 1977-12-27 US claimed