Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K11 | Q16584 | 7/20 | 0.69 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | TNIK | Q9UKE5 | 10/20 | 0.61 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.54 |
| ▸ | IGF1R | P08069 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL720216 | 0.86 | MAP3K11 (0.82) | MAP3K11MAP3K9MAPK1TNIKMAP4K1 | |
| SCHEMBL7900013 | 0.85 | MAP3K11 (0.58) | MAP3K11MAP3K9MAPK1TNIKMAP4K1 | |
| SCHEMBL24535333 | 0.85 | MAP3K11 (0.75) | MAP3K11MAP3K9MAPK1TNIKMAP4K1 | |
| SCHEMBL22336562 | 0.84 | MAP3K11 (0.82) | MAP3K11MAP3K9MAPK1TNIKMAP4K1 | |
| SCHEMBL24535576 | 0.82 | MAP3K11 (0.72) | MAP3K11MAP3K9MAPK1TNIKMAP4K1 | |
| SCHEMBL22336544 | 0.82 | MAP3K11 (1.00) | MAP3K11MAP3K9MAPK1TNIKMAP4K1 | |
| SCHEMBL22336543 | 0.81 | MAP3K11 (0.79) | MAP3K11MAP3K9MAPK1TNIKMAP4K1 | |
| SCHEMBL22336909 | 0.81 | MAP3K11 (0.45) | MAP3K11MAP3K9MAPK1TNIK | |
| SCHEMBL22336737 | 0.81 | MAP3K11 (0.78) | MAP3K11MAP3K9MAPK1TNIKMAP4K1 | |
| Trifluoroacetic Acid SCHEMBL22324678 | 0.80 | MAP3K11 (0.69) | MAP3K11MAP3K9MAPK1TNIKIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163594-A1 | IMMUNOPHILIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-08-13 | — | — | WO | disclosed |
| WO-2020163598-A1 | IMMUNOPHILIN-DEPENDENT INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-08-13 | — | — | WO | disclosed |
| WO-2020163598-A1 | IMMUNOPHILIN-DEPENDENT INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-08-13 | — | — | WO | disclosed |