Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K11 | Q16584 | 3/20 | 0.45 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | TNIK | Q9UKE5 | 4/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.39 |
| ▸ | VEGFA | P15692 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CCNK | O75909 | 1/20 | 0.37 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.37 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20634236 | 0.85 | MAP3K11 (0.58) | MAP3K11MAP3K9MAPK1TNIKKCNH2 | |
| SCHEMBL22324681 | 0.83 | PTPN11 (0.47) | MAP3K11MAP3K9MAPK1ADORA2ATNIK | |
| SCHEMBL22324673 | 0.81 | MAP3K11 (0.69) | MAP3K11MAP3K9MAPK1TNIK | |
| SCHEMBL25153562 | 0.76 | CHEK1 (0.39) | — | |
| SCHEMBL20634857 | 0.75 | MAP3K11 (0.49) | MAP3K11MAP3K9MAPK1TNIKKCNH2 | |
| SCHEMBL3155717 | 0.72 | MEN1 (0.58) | ADORA2AVEGFAEGLN1TP53THRB | |
| SCHEMBL32667348 | 0.72 | VEGFA (0.64) | VEGFAEGLN1TP53THRBSMN1; SMN2 | |
| SCHEMBL11932534 | 0.72 | FAAH (0.57) | VEGFAEGLN1TP53THRB | |
| SCHEMBL29914660 | 0.70 | HRH3 (0.50) | TBK1VEGFAEGLN1SUCNR1 | |
| SCHEMBL22971783 | 0.70 | MAP3K11 (0.51) | MAP3K11MAP3K9MAPK1TNIKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163594-A1 | IMMUNOPHILIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-08-13 | — | — | WO | disclosed |
| WO-2020163598-A1 | IMMUNOPHILIN-DEPENDENT INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-08-13 | — | — | WO | disclosed |