SCHEMBL22324733

SCHEMBL22324733

O=C(O)C1CCCC2C1CCC1C3CCC4CCCCC4C3CCC21

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PEPD P12955 1/20 0.37
MEN1 O00255 1/20 0.34
BLM P54132 1/20 0.34
KMT2A Q03164 1/20 0.34
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
HSD11B1 P28845 1/20 0.32
HSD11B2 P80365 1/20 0.32
SLC1A2 P43004 1/20 0.32
SLC1A1 P43005 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18532463 0.87 PEPD (0.42) PEPDMEN1BLMKMT2AALDH1A1
SCHEMBL7734513 0.87 PEPD (0.42) PEPDMEN1BLMKMT2AALDH1A1
SCHEMBL195046 0.87 PEPD (0.42) PEPDMEN1BLMKMT2AALDH1A1
SCHEMBL4766405 0.87 PEPD (0.42) PEPDMEN1BLMKMT2AALDH1A1
SCHEMBL14529590 0.87 MEN1 (0.39) PEPDMEN1BLMKMT2AALDH1A1
SCHEMBL11405911 0.86 HSD11B1 (0.33) HSD11B1HSD11B2
SCHEMBL7768150 0.85 PEPD (0.41) PEPDMEN1BLMKMT2AALDH1A1
SCHEMBL9419364 0.85 MEN1 (0.42) PEPDMEN1BLMKMT2AALDH1A1
SCHEMBL55536 0.85 PEPD (0.41) PEPDMEN1BLMKMT2AALDH1A1
SCHEMBL7598028 0.85 PEPD (0.41) PEPDMEN1BLMKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118339274-A Brandy replica 艾娃食品实验室股份有限公司 2024-07-12 CN disclosed
EP-3921327-A1 GLYCYRRHETINIC ACID DERIVATIVES FOR USE IN TREATING HYPERKALEMIA Ardelyx, Inc. (US) 2021-12-15 EP disclosed
WO-2020163642-A1 GLYCYRRHETINIC ACID DERIVATIVES FOR USE IN TREATING HYPERKALEMIA ARDELYX, INC. (US) 2020-08-13 WO disclosed