Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22335662 | 0.83 | CYP4A11 (0.47) | CYP4A11CYP4F2POLBMAPK1PTGER4 | |
| SCHEMBL8825162 | 0.81 | KDM4E (0.49) | KDM4EL3MBTL1MAPK1PTGER4MRGPRX4 | |
| SCHEMBL23704524 | 0.79 | L3MBTL1 (0.42) | KDM4EL3MBTL1MAPK1PTGER4MRGPRX4 | |
| SCHEMBL22335921 | 0.74 | CYP4A11 (0.47) | CYP4A11CYP4F2KDM4EPOLBHDAC1 | |
| SCHEMBL5434765 | 0.72 | MEN1 (0.41) | MAPK1PTGER4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7226331 | 0.72 | KDM4E (0.47) | KDM4EL3MBTL1MAPK1PTGER4SMN1; SMN2 | |
| SCHEMBL14918993 | 0.72 | KDM4E (0.71) | KDM4EL3MBTL1MAPK1MRGPRX4MEN1 | |
| SCHEMBL22335799 | 0.71 | CYP1A2 (0.51) | CYP4A11CYP4F2KDM4EPOLBPKM | |
| SCHEMBL22335925 | 0.71 | CYP4A11 (0.60) | CYP4A11CYP4F2KDM4EL3MBTL1POLB | |
| SCHEMBL31753771 | 0.71 | CYP4A11 (0.60) | CYP4A11CYP4F2KDM4EL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020162612-A1 | PYRIDINE COMPOUND SUBSTITUTED BY HETEROARYL | 大正製薬株式会社 | 2020-08-13 | — | — | WO | disclosed |