Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | RGS12 | O14924 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2236515 | 0.85 | THRA (0.40) | KDM4ESMN1; SMN2POLBKMT2AMEN1 | |
| SCHEMBL2232569 | 0.81 | MAPT (0.54) | PABPC1MAPTALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL2230605 | 0.80 | PPARG (0.43) | MAPTALDH1A1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL3128839 | 0.79 | HSPB1 (0.52) | PABPC1MAPTALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL2232561 | 0.75 | MAPT (0.47) | PABPC1MAPTALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL2236528 | 0.74 | THRA (0.41) | KDM4EHSPB1LMNAHTTRAB9A | |
| SCHEMBL14108436 | 0.73 | MAPT (0.51) | PABPC1MAPTALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL13581938 | 0.73 | MAPT (0.51) | PABPC1MAPTALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL13581940 | 0.73 | MAPT (0.51) | PABPC1MAPTALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL13742200 | 0.72 | MAPT (0.50) | PABPC1MAPTALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011093524-A1 | DI - SUBSTITUTED PYRIDINE DERIVATIVES AS ANTICANCERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-08-04 | — | — | WO | disclosed |