Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | STAT3 | P40763 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Avicequinone C SCHEMBL30589989 | 0.83 | STAT3 (0.57) | ALDH1A1STAT3NPC1RAB9AL3MBTL1 | |
| SCHEMBL22325630 | 0.81 | STAT3 (0.61) | ALDH1A1STAT3KMT2AMEN1CDC25B | |
| SCHEMBL18123770 | 0.81 | ALDH1A1 (0.50) | ALDH1A1STAT3NPC1RAB9AL3MBTL1 | |
| SCHEMBL6577994 | 0.73 | STAT3 (0.61) | ALDH1A1STAT3NPC1RAB9AL3MBTL1 | |
| SCHEMBL16167166 | 0.73 | STAT3 (0.56) | ALDH1A1STAT3NPC1RAB9APLA2G1B | |
| SCHEMBL22325627 | 0.72 | ALDH1A1 (0.56) | ALDH1A1STAT3NPC1RAB9AL3MBTL1 | |
| SCHEMBL45647 | 0.72 | STAT3 (0.47) | ALDH1A1STAT3NPC1RAB9AL3MBTL1 | |
| SCHEMBL19669614 | 0.72 | STAT3 (0.59) | ALDH1A1STAT3NPC1RAB9AL3MBTL1 | |
| SCHEMBL1887185 | 0.70 | STAT3 (0.69) | ALDH1A1STAT3NPC1RAB9AL3MBTL1 | |
| SCHEMBL30422 | 0.70 | STAT3 (0.57) | ALDH1A1STAT3NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020161959-A1 | NAPHTHOQUINONE COMPOUND HAVING ANTIBACTERIAL AND ANTIVIRAL ACTIVITIES AND PHARMACEUTICAL USE THEREOF | タヒボジャパン株式会社 | 2020-08-13 | — | — | WO | disclosed |