Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | USP1 | O94782 | 2/20 | 0.41 |
| ▸ | USP19 | O94966 | 2/20 | 0.41 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28705 | 0.76 | STAT3 (0.56) | STAT3ALDH1A1MEN1KMT2ACDC25B | |
| SCHEMBL6577994 | 0.76 | STAT3 (0.61) | STAT3ALDH1A1MEN1KMT2ACDC25B | |
| SCHEMBL22325627 | 0.76 | ALDH1A1 (0.56) | STAT3ALDH1A1MEN1KMT2ACDC25B | |
| SCHEMBL19669614 | 0.74 | STAT3 (0.59) | STAT3ALDH1A1MEN1KMT2ACDC25B | |
| SCHEMBL22730655 | 0.74 | PTPRC (0.38) | STAT3ALDH1A1MEN1KMT2ABCL2 | |
| SCHEMBL1887185 | 0.73 | STAT3 (0.69) | STAT3ALDH1A1MEN1KMT2ACDC25B | |
| SCHEMBL30422 | 0.73 | STAT3 (0.57) | STAT3ALDH1A1MEN1KMT2ACDC25B | |
| SCHEMBL12640092 | 0.73 | STAT3 (0.53) | STAT3ALDH1A1MEN1KMT2ACDC25B | |
| SCHEMBL18691830 | 0.73 | STAT3 (0.53) | STAT3ALDH1A1MEN1KMT2ACDC25B | |
| SCHEMBL10068407 | 0.73 | ALDH1A1 (0.53) | STAT3ALDH1A1MEN1KMT2ACDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2983790-A2 | METHODS FOR TREATING CANCER | Boston Biomedical, Inc. (US) | 2016-02-17 | — | — | EP | disclosed |
| WO-2014169078-A2 | METHODS FOR TREATING CANCER | BOSTON BIOMEDICAL, INC. (US) | 2014-10-16 | — | — | WO | disclosed |