Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22325961 | 0.95 | ALDH1A1 (0.41) | ALDH1A1TDP1TSHRCYP3A4TP53 | |
| SCHEMBL22325934 | 0.92 | ALDH1A1 (0.40) | ALDH1A1TDP1TSHRCYP3A4TP53 | |
| SCHEMBL15774527 | 0.80 | HTT (0.46) | ALDH1A1TDP1TSHRCYP3A4SMN1; SMN2 | |
| SCHEMBL22325996 | 0.79 | ALDH1A1 (0.43) | ALDH1A1TDP1TSHRCYP3A4SMN1; SMN2 | |
| SCHEMBL22325836 | 0.77 | CD44 (0.45) | ALDH1A1TDP1TSHRCYP3A4TP53 | |
| SCHEMBL22325952 | 0.76 | EPAS1 (0.46) | ALDH1A1TDP1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL22325935 | 0.76 | ALDH1A1 (0.39) | ALDH1A1TDP1TSHRTP53SMN1; SMN2 | |
| SCHEMBL22325766 | 0.75 | MEN1 (0.40) | ALDH1A1TDP1TSHRCYP3A4SMN1; SMN2 | |
| SCHEMBL29278446 | 0.75 | MAPT (0.44) | ALDH1A1TDP1CYP3A4MAPTKMT2A | |
| SCHEMBL22326087 | 0.74 | PDE7A (0.42) | ALDH1A1TDP1SMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020162471-A1 | PYRIDONE DERIVATIVE | マルホ株式会社 | 2020-08-13 | — | — | WO | disclosed |