Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22326003 | 0.92 | ALDH1A1 (0.46) | ALDH1A1TDP1TSHRCYP3A4TP53 | |
| SCHEMBL22325961 | 0.88 | ALDH1A1 (0.41) | ALDH1A1TDP1TSHRCYP3A4TP53 | |
| SCHEMBL22326076 | 0.82 | CA12 (0.40) | ALDH1A1TDP1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL22325935 | 0.82 | ALDH1A1 (0.39) | ALDH1A1TDP1TSHRTP53SMN1; SMN2 | |
| SCHEMBL239430 | 0.80 | MEN1 (0.41) | ALDH1A1TDP1TSHRCYP3A4TP53 | |
| SCHEMBL22325855 | 0.79 | EPAS1 (0.44) | ALDH1A1TDP1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL22326089 | 0.78 | PDE7A (0.37) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL15774527 | 0.74 | HTT (0.46) | ALDH1A1TDP1TSHRCYP3A4SMN1; SMN2 | |
| SCHEMBL22325996 | 0.73 | ALDH1A1 (0.43) | ALDH1A1TDP1TSHRCYP3A4SMN1; SMN2 | |
| SCHEMBL22325836 | 0.71 | CD44 (0.45) | ALDH1A1TDP1TSHRCYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020162471-A1 | PYRIDONE DERIVATIVE | マルホ株式会社 | 2020-08-13 | — | — | WO | disclosed |