Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2635654 | 0.87 | ALDH1A1 (0.72) | ALDH1A1HTTKMT2AKDM4EMEN1 | |
| SCHEMBL214187 | 0.86 | ALDH1A1 (0.56) | ALDH1A1HTTKMT2AKDM4EMEN1 | |
| SCHEMBL30952856 | 0.85 | ALDH1A1 (0.54) | ALDH1A1HTTKMT2AKDM4EMEN1 | |
| SCHEMBL5799758 | 0.83 | ALDH1A1 (0.54) | ALDH1A1HTTKMT2AKDM4EMEN1 | |
| SCHEMBL30938979 | 0.82 | ALDH1A1 (0.52) | ALDH1A1HTTKMT2AKDM4EMEN1 | |
| SCHEMBL22325959 | 0.81 | ALDH1A1 (0.41) | ALDH1A1HTTKMT2AKDM4EMEN1 | |
| SCHEMBL5417319 | 0.81 | KMT2A (0.55) | ALDH1A1HTTKMT2AKDM4EMEN1 | |
| SCHEMBL214562 | 0.81 | DDB1 (0.51) | ALDH1A1HTTKMT2AKDM4EMEN1 | |
| SCHEMBL29893813 | 0.80 | ALDH1A1 (0.41) | ALDH1A1HTTKMT2AKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL214478 | 0.80 | DDB1 (0.50) | ALDH1A1HTTKMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020162471-A1 | PYRIDONE DERIVATIVE | マルホ株式会社 | 2020-08-13 | — | — | WO | disclosed |
| CN-1922141-A | Novel heterocyclic compound | DAINIPPON SUMITOMO PHARMA CO (JP) | 2007-02-28 | — | — | CN | disclosed |