Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 2/20 | 0.50 |
| ▸ | TYR | P14679 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | FOS | P01100 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | JUN | P05412 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28507984 | 0.87 | TSHR (0.56) | TSHRCYP3A4BLMNFKB1NPSR1 | |
| SCHEMBL7128355 | 0.86 | TSHR (0.58) | TSHRCYP3A4BLMNFKB1NPSR1 | |
| SCHEMBL22208556 | 0.81 | TSHR (0.61) | TSHRCYP3A4BLMNFKB1NPSR1 | |
| SCHEMBL20563424 | 0.80 | TSHR (0.65) | TSHRCYP3A4BLMNFKB1NPSR1 | |
| SCHEMBL1595549 | 0.80 | TSHR (0.65) | TSHRCYP3A4BLMNFKB1NPSR1 | |
| SCHEMBL30343472 | 0.80 | TSHR (0.65) | TSHRCYP3A4BLMNFKB1NPSR1 | |
| SCHEMBL21852873 | 0.79 | TSHR (0.62) | TSHRCYP3A4BLMNFKB1NPSR1 | |
| SCHEMBL29625307 | 0.79 | TSHR (0.62) | TSHRCYP3A4BLMNFKB1NPSR1 | |
| SCHEMBL7901872 | 0.79 | TSHR (0.68) | TSHRCYP3A4BLMNFKB1NPSR1 | |
| SCHEMBL2411502 | 0.79 | TSHR (0.62) | TSHRCYP3A4BLMNFKB1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020162408-A1 | METHOD FOR PRODUCING 1,1,1-TRIFLUORO-2,2-BISARYLETHANE, AND 1,1,1-TRIFLUORO-2,2-BISARYLETHANE | セントラル硝子株式会社 | 2020-08-13 | — | — | WO | claimed |
| US-12435185-B2 | Method for producing 1,1,1-trifluoro-2,2-bisarylethane, and 1,1,1-trifluoro-2,2-bisarylethane | CENTRAL GLASS COMPANY, LIMITED (JP) | 2025-10-07 | — | — | US | disclosed |
| US-20220106444-A1 | Method for Producing 1,1,1-Trifluoro-2,2-Bisarylethane, and 1,1,1-Trifluoro-2,2-Bisarylethane | CENTRAL GLASS COMPANY, LIMITED (JP) | 2022-04-07 | — | — | US | disclosed |
| WO-2020162408-A1 | METHOD FOR PRODUCING 1,1,1-TRIFLUORO-2,2-BISARYLETHANE, AND 1,1,1-TRIFLUORO-2,2-BISARYLETHANE | セントラル硝子株式会社 | 2020-08-13 | — | — | WO | disclosed |
| WO-2020162408-A1 | METHOD FOR PRODUCING 1,1,1-TRIFLUORO-2,2-BISARYLETHANE, AND 1,1,1-TRIFLUORO-2,2-BISARYLETHANE | セントラル硝子株式会社 | 2020-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220106444-A1 | Method for Producing 1,1,1-Trifluoro-2,2-Bisarylethane, and 1,1,1-Trifluoro-2,2-Bisarylethane | NAF1, FXR1, AFF1 | TSHR 1232/4885CYP3A4 1051/4885BLM 614/4885 |
| US-12435185-B2 | Method for producing 1,1,1-trifluoro-2,2-bisarylethane, and 1,1,1-trifluoro-2,2-bisarylethane | NAF1, FXR1, AFF1 | TSHR 1232/4885CYP3A4 1051/4885BLM 614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.