Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | BLM | P54132 | 2/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.64 |
| ▸ | TUBB | P07437 | 2/20 | 0.64 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.64 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.64 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.64 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.64 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.64 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.64 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.64 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.64 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.64 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.64 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.64 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.64 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17384090 | 0.92 | TSHR (0.64) | TSHRCYP3A4BLMNFKB1NPSR1 | |
| SCHEMBL16174343 | 0.92 | TSHR (0.64) | TSHRCYP3A4BLMNFKB1NPSR1 | |
| SCHEMBL17832173 | 0.91 | TUBB4A (0.59) | TSHRCYP3A4BLMNFKB1NPSR1 | |
| SCHEMBL19728205 | 0.91 | TSHR (0.58) | TSHRCYP3A4BLMNFKB1NPSR1 | |
| SCHEMBL11197069 | 0.90 | TSHR (0.62) | TSHRCYP3A4BLMNFKB1NPSR1 | |
| SCHEMBL705159 | 0.88 | TSHR (0.68) | TSHRCYP3A4BLMNFKB1NPSR1 | |
| SCHEMBL29466173 | 0.86 | TSHR (0.66) | TSHRCYP3A4BLMNFKB1NPSR1 | |
| SCHEMBL1301569 | 0.86 | TSHR (0.66) | TSHRCYP3A4BLMNFKB1NPSR1 | |
| SCHEMBL15553306 | 0.86 | TSHR (0.66) | TSHRCYP3A4BLMNFKB1NPSR1 | |
| SCHEMBL12512568 | 0.86 | TSHR (0.61) | TSHRCYP3A4BLMNFKB1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194019-B1 | ORGANOLEPTIC 1,2-DIOL DISUBSTITUTED WITH PHENYL, CYCLOHEXYL, OR BENZODIOXOLE RINGS; FOODS, TOBACCO; MASKING SMOKE ODORS | GIVAUDAN S.A. (CH) | 2001-02-27 | — | — | US | claimed |
| EP-0746986-B1 | Delayed release flavourant compositions | GIVAUDAN ROURE INT (CH) | 2000-08-23 | — | — | EP | claimed |
| US-5904148-A | Delayed release flavorant compositions | GIVADUAN-ROURE (INTERNATIONAL) SA (CH) | 1999-05-18 | — | — | US | claimed |
| EP-0746986-A2 | Delayed release flavourant compositions | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1996-12-11 | — | — | EP | claimed |
| US-20170362152-A1 | NOVEL 1,2-DIPHENYLETHYLENE GLYCOL COMPOUNDS FOR COMBATING AGING OF THE SKIN, AND COSMETIC USE THEREOF | L'OREAL (FR) | 2017-12-21 | — | — | US | disclosed |
| US-20170362152-A1 | NOVEL 1,2-DIPHENYLETHYLENE GLYCOL COMPOUNDS FOR COMBATING AGING OF THE SKIN, AND COSMETIC USE THEREOF | L'OREAL (FR) | 2017-12-21 | — | — | US | disclosed |
| WO-2016092076-A1 | NOVEL 1,2-DIPHENYLETHYLENE GLYCOL COMPOUNDS FOR COMBATING AGING OF THE SKIN, AND COSMETIC USE THEREOF | L'OREAL (FR) | 2016-06-16 | — | — | WO | disclosed |
| US-6194019-B1 | ORGANOLEPTIC 1,2-DIOL DISUBSTITUTED WITH PHENYL, CYCLOHEXYL, OR BENZODIOXOLE RINGS; FOODS, TOBACCO; MASKING SMOKE ODORS | GIVAUDAN S.A. (CH) | 2001-02-27 | — | — | US | disclosed |
| EP-0746986-B1 | Delayed release flavourant compositions | GIVAUDAN ROURE INT (CH) | 2000-08-23 | — | — | EP | disclosed |
| US-5921247-A | Delayed release flavorant compositions | GIVAUDAN-ROURE (INTERNATIONAL) SA (CH) | 1999-07-13 | — | — | US | disclosed |
| US-5904148-A | Delayed release flavorant compositions | GIVADUAN-ROURE (INTERNATIONAL) SA (CH) | 1999-05-18 | — | — | US | disclosed |
| EP-0746986-A2 | Delayed release flavourant compositions | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1996-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362152-A1 | NOVEL 1,2-DIPHENYLETHYLENE GLYCOL COMPOUNDS FOR COMBATING AGING OF THE SKIN, AND COSMETIC USE THEREOF | GLA, DSG1, GPX1 | TSHR 4480/4885CYP3A4 4481/4885BLM 2743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.