Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13028693 | 0.90 | TSHR (0.50) | L3MBTL1TSHRALDH1A1SMN1; SMN2HTT | |
| SCHEMBL12622696 | 0.83 | TSHR (0.47) | L3MBTL1TSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL15884132 | 0.81 | L3MBTL1 (0.51) | NAAAL3MBTL1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL22326308 | 0.81 | L3MBTL1 (0.51) | NAAAL3MBTL1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL25533030 | 0.81 | L3MBTL1 (0.51) | NAAAL3MBTL1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL26813320 | 0.81 | L3MBTL1 (0.51) | NAAAL3MBTL1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL20534920 | 0.81 | L3MBTL1 (0.51) | NAAAL3MBTL1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL16346595 | 0.81 | L3MBTL1 (0.51) | NAAAL3MBTL1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL4963940 | 0.81 | NAAA (0.53) | NAAAL3MBTL1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL3543002 | 0.81 | NAAA (0.53) | NAAAL3MBTL1TSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020162725-A1 | TARGET PROTEIN EED DEGRADATION-INDUCING DEGRADUCER, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DISEASES RELATED TO EED, EZH2, OR PRC2, COMPRISING SAME AS ACTIVE INGREDIENT | 한국화학연구원 | 2020-08-13 | — | — | WO | disclosed |