Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 13/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22326245 | 0.98 | PAOX (0.38) | PAOXEPHX2CYP2C19GAA | |
| SCHEMBL25369676 | 0.96 | PAOX (0.39) | PAOXEPHX2CYP2C19GAA | |
| SCHEMBL21069585 | 0.93 | PAOX (0.50) | PAOXEPHX2CYP2C19 | |
| SCHEMBL21069308 | 0.93 | PAOX (0.50) | PAOXEPHX2CYP2C19 | |
| SCHEMBL28453694 | 0.92 | TSHR (0.36) | PAOX | |
| SCHEMBL12080215 | 0.92 | TSHR (0.36) | PAOX | |
| SCHEMBL22326140 | 0.91 | PAOX (0.52) | PAOXCYP2C19GAA | |
| SCHEMBL21071023 | 0.91 | PAOX (0.52) | PAOXCYP2C19GAA | |
| SCHEMBL20819275 | 0.90 | TSHR (0.36) | PAOXGAA | |
| SCHEMBL22326246 | 0.85 | TLR2 (0.43) | PAOXEPHX2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3922632-A1 | TARGET PROTEIN EED DEGRADATION-INDUCING DEGRADUCER, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DISEASES RELATED TO EED, EZH2, OR PRC2, COMPRISING SAME AS ACTIVE INGREDIENT | Korea Research Institute of Chemical Technology (KR) | 2021-12-15 | — | — | EP | disclosed |
| WO-2020162725-A1 | TARGET PROTEIN EED DEGRADATION-INDUCING DEGRADUCER, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DISEASES RELATED TO EED, EZH2, OR PRC2, COMPRISING SAME AS ACTIVE INGREDIENT | 한국화학연구원 | 2020-08-13 | — | — | WO | disclosed |