Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 6/20 | 0.43 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | EPOR | P19235 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27160303 | 0.98 | TLR2 (0.41) | TLR2PAOXSMN1; SMN2MEN1KMT2A | |
| SCHEMBL21069308 | 0.93 | PAOX (0.50) | TLR2PAOXMEN1KMT2AALDH1A1 | |
| SCHEMBL21069585 | 0.93 | PAOX (0.50) | TLR2PAOXMEN1KMT2AALDH1A1 | |
| SCHEMBL19586455 | 0.92 | SMN1; SMN2 (0.42) | TLR2PAOXSMN1; SMN2MEN1KMT2A | |
| SCHEMBL22326140 | 0.91 | PAOX (0.52) | TLR2PAOXMEN1KMT2AALDH1A1 | |
| SCHEMBL21071023 | 0.91 | PAOX (0.52) | TLR2PAOXMEN1KMT2AALDH1A1 | |
| SCHEMBL22326266 | 0.85 | PAOX (0.41) | PAOXGAAEPHX2 | |
| SCHEMBL2330619 | 0.85 | PAOX (0.39) | TLR2PAOXSMN1; SMN2ALDH1A1RECQL | |
| SCHEMBL21806080 | 0.85 | PAOX (0.39) | TLR2PAOXSMN1; SMN2ALDH1A1RECQL | |
| SCHEMBL26923885 | 0.85 | SMN1; SMN2 (0.38) | TLR2PAOXSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240201196-A1 | NON-COVALENT HALOTAG LIGANDS | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e. V. (DE) | 2024-06-20 | — | — | US | disclosed |
| EP-4330333-A2 | NON-COVALENT HALOTAG LIGANDS | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2024-03-06 | — | — | EP | disclosed |
| WO-2020162725-A1 | TARGET PROTEIN EED DEGRADATION-INDUCING DEGRADUCER, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DISEASES RELATED TO EED, EZH2, OR PRC2, COMPRISING SAME AS ACTIVE INGREDIENT | 한국화학연구원 | 2020-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240201196-A1 | NON-COVALENT HALOTAG LIGANDS | HDHD5, DIMT1, METTL14 | TLR2 4292/4885PAOX 3961/4885SMN1; SMN2 4860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.