Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Chloroform. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloroform SCHEMBL540543 | 0.91 | — | — | |
| Chloroform SCHEMBL9583965 | 0.91 | — | — | |
| Chloroform SCHEMBL9752850 | 0.91 | — | — | |
| Chloroform SCHEMBL9752848 | 0.91 | LMNA (0.80) | — | |
| Chloroform SCHEMBL9310908 | 0.91 | — | — | |
| Chloroform SCHEMBL27674735 | 0.83 | — | — | |
| Chloroform SCHEMBL28044218 | 0.83 | — | — | |
| Chloroform SCHEMBL1014755 | 0.83 | — | — | |
| Chloroform SCHEMBL28204134 | 0.83 | — | — | |
| Chloroform SCHEMBL16014083 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020162705-A1 | TOLL-LIKE RECEPTOR 7 OR 8 AGONIST-CHOLESTEROL COMPLEX, AND USE OF SAME | 성균관대학교산학협력단 | 2020-08-13 | — | — | WO | disclosed |