Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Chloroform. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloroform SCHEMBL9752848 | 1.00 | LMNA (0.80) | — | |
| Chloroform SCHEMBL9583965 | 1.00 | — | — | |
| Chloroform SCHEMBL28204134 | 0.91 | — | — | |
| Chloroform SCHEMBL22326330 | 0.91 | — | — | |
| Chloroform SCHEMBL16014083 | 0.91 | — | — | |
| Chloroform SCHEMBL10950487 | 0.89 | LMNA (1.00) | — | |
| Chloroform SCHEMBL30536988 | 0.89 | — | — | |
| Chloroform SCHEMBL2084455 | 0.89 | — | — | |
| Chloroform SCHEMBL88 | 0.89 | — | — | |
| Chloroform SCHEMBL11043408 | 0.89 | LMNA (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009823-A1 | PHOTOCATALYTIC PROCESS FOR DEGRADATION OF ORGANIC MATERIALS IN A VAPORIZED OR GASEOUS STATE | TRUSTEES OF BOSTON UNIVERSITY (US) | 1991-07-11 | — | — | WO | disclosed |
| EP-0365615-A4 | CATALYTIC PROCESS FOR DEGRADATION OF ORGANIC MATERIALS IN AQUEOUS AND ORGANIC FLUIDS TO PRODUCE ENVIRONMENTALLY COMPATIBLE PRODUCTS. | UNIV BOSTON (US) | 1990-06-27 | — | — | EP | disclosed |
| EP-0365615-A1 | CATALYTIC PROCESS FOR DEGRADATION OF ORGANIC MATERIALS IN AQUEOUS AND ORGANIC FLUIDS TO PRODUCE ENVIRONMENTALLY COMPATIBLE PRODUCTS. | UNIV BOSTON (US) | 1990-05-02 | — | — | EP | disclosed |
| WO-1989008079-A1 | CATALYTIC PROCESS FOR DEGRADATION OF ORGANIC MATERIALS IN AQUEOUS AND ORGANIC FLUIDS TO PRODUCE ENVIRONMENTALLY COMPATIBLE PRODUCTS | TRUSTEES OF BOSTON UNIVERSITY (US) | 1989-09-08 | — | — | WO | disclosed |