Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 5/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14048611 | 1.00 | LSS (0.54) | LSSCYP1A2S1PR1S1PR3S1PR5 | |
| Iodide SCHEMBL23004271 | 0.98 | LSS (0.53) | LSSCYP1A2S1PR1S1PR3S1PR5 | |
| Bromide SCHEMBL23004523 | 0.98 | LSS (0.53) | LSSCYP1A2S1PR1S1PR3S1PR5 | |
| Hydrochloric Acid SCHEMBL23004257 | 0.98 | LSS (0.53) | LSSCYP1A2S1PR1S1PR3S1PR5 | |
| SCHEMBL19454711 | 0.98 | LSS (0.51) | LSSCYP1A2S1PR1S1PR3S1PR5 | |
| SCHEMBL24948221 | 0.94 | CYP1A2 (0.50) | LSSCYP1A2S1PR1S1PR3S1PR5 | |
| SCHEMBL8507191 | 0.92 | CYP1A2 (0.56) | LSSCYP1A2BCHEGNAO1GNAI3 | |
| SCHEMBL19674057 | 0.90 | CYP1A2 (0.54) | LSSCYP1A2S1PR1S1PR3S1PR5 | |
| Fluoride SCHEMBL30330840 | 0.90 | CYP1A2 (0.54) | LSSCYP1A2BCHEGNAO1GNAI3 | |
| Thiocyanic Acid SCHEMBL23004325 | 0.90 | LSS (0.47) | LSSCYP1A2S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10736904-B2 | Thienopyrimidine derivatives, processes for the preparation thereof and therapeutic uses thereof | SANOFI (FR) | 2020-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10736904-B2 | Thienopyrimidine derivatives, processes for the preparation thereof and therapeutic uses thereof | DPYD, TYMP, DHFR | LSS 1851/4885CYP1A2 10/4885S1PR1 1009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.