Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 6/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22326391 | 0.98 | LSS (0.54) | LSSCYP1A2S1PR1S1PR3S1PR5 | |
| SCHEMBL14048611 | 0.98 | LSS (0.54) | LSSCYP1A2S1PR1S1PR3S1PR5 | |
| Hydrochloric Acid SCHEMBL23004257 | 0.96 | LSS (0.53) | LSSCYP1A2S1PR1S1PR3S1PR5 | |
| Bromide SCHEMBL23004523 | 0.96 | LSS (0.53) | LSSCYP1A2S1PR1S1PR3S1PR5 | |
| SCHEMBL19454711 | 0.96 | LSS (0.51) | LSSCYP1A2S1PR1S1PR3S1PR5 | |
| SCHEMBL24948221 | 0.93 | CYP1A2 (0.50) | LSSCYP1A2S1PR1S1PR3S1PR5 | |
| SCHEMBL8507191 | 0.90 | CYP1A2 (0.56) | LSSCYP1A2BCHEGNAO1GNAI3 | |
| Iodide SCHEMBL15008877 | 0.89 | GNAO1 (0.47) | LSSCYP1A2GNAO1GNAI3GNAI1 | |
| Iodide SCHEMBL15008979 | 0.89 | GNAO1 (0.47) | LSSCYP1A2GNAO1GNAI3GNAI1 | |
| Iodide SCHEMBL15008244 | 0.89 | GNAO1 (0.47) | LSSCYP1A2GNAO1GNAI3GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11623971-B2 | Freestanding ion gel and method for preparing the same | Research & Business Foundation Sungkyunkwan University (KR) | 2023-04-11 | — | — | US | disclosed |
| US-20210054127-A1 | FREESTANDING ION GEL AND METHOD FOR PREPARING THE SAME | Research & Business Foundation Sungkyunkwan University (KR) | 2021-02-25 | — | — | US | disclosed |