Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 7/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12561561 | 0.93 | CYP1A2 (0.52) | LSSCYP1A2BCHEBACE1 | |
| Hydrochloric Acid SCHEMBL30330784 | 0.91 | CYP1A2 (0.50) | LSSCYP1A2BCHEGNAO1BACE1 | |
| SCHEMBL28290737 | 0.88 | BCHE (0.55) | LSSBCHEGNAO1BACE1GNAI3 | |
| SCHEMBL12558281 | 0.87 | LSS (0.44) | LSSCYP1A2GNAO1MEN1HTT | |
| SCHEMBL25653931 | 0.86 | BCHE (0.53) | LSSCYP1A2BCHEGNAO1BACE1 | |
| SCHEMBL10646171 | 0.86 | LSS (0.48) | LSSCYP1A2BCHE | |
| SCHEMBL14400435 | 0.85 | HSD11B1 (0.38) | LSSCYP1A2 | |
| SCHEMBL29265396 | 0.83 | LSS (0.47) | LSSCYP1A2BCHEGNAO1MEN1 | |
| Hydrochloric Acid SCHEMBL30212673 | 0.83 | HSD11B1 (0.37) | CYP1A2 | |
| Fluoride SCHEMBL30330649 | 0.83 | HSD11B1 (0.37) | LSSCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10736904-B2 | Thienopyrimidine derivatives, processes for the preparation thereof and therapeutic uses thereof | SANOFI (FR) | 2020-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10736904-B2 | Thienopyrimidine derivatives, processes for the preparation thereof and therapeutic uses thereof | DPYD, TYMP, DHFR | LSS 1851/4885CYP1A2 10/4885BCHE 1486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.