SCHEMBL22326492

SCHEMBL22326492

CCOC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@H](OC)[C@@H]1O

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.54
SLC28A2 O43868 1/20 0.54
SLC29A1 Q99808 1/20 0.54
SLC28A3 Q9HAS3 1/20 0.54
P2RY6 Q15077 11/20 0.53
P2RY2 P41231 11/20 0.53
P2RY4 P51582 6/20 0.53
P2RY14 Q15391 5/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17577501 0.90 SLC28A1 (0.57) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL383249 0.90 SLC28A1 (0.57) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL26554037 0.89 SLC28A1 (0.58) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL121732 0.89 SLC28A1 (0.69) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL19399430 0.89 SLC28A1 (0.58) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL12259056 0.89 SLC28A1 (0.69) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL16940283 0.89 SLC28A1 (0.58) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL21563023 0.89 SLC28A1 (0.58) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL25966278 0.89 SLC28A1 (0.58) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL24879407 0.88 SLC28A1 (0.55) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10738308-B2 Short interfering nucleic acid (siNA) molecules containing a 2′ internucleoside linkage (3dT) SIRNA THERAPEUTICS, INC. (US) 2020-08-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10738308-B2 Short interfering nucleic acid (siNA) molecules containing a 2′ internucleoside linkage (3dT) SIN3A, NSUN3, AGO2 SLC28A1 378/4885SLC28A2 361/4885SLC29A1 993/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.