Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.31 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.30 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.30 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.30 |
| ▸ | KMO | O15229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20174371 | 0.90 | CYP1A1 (0.36) | PIM1CYP1A2CYP1A1CYP1B1ALDH1A1 | |
| SCHEMBL20174362 | 0.90 | CYP1A1 (0.38) | PIM1CYP1A2CYP1A1CYP1B1ALDH1A1 | |
| SCHEMBL20174368 | 0.90 | CYP1A1 (0.38) | PIM1CYP1A2CYP1A1CYP1B1ALDH1A1 | |
| SCHEMBL22326551 | 0.89 | PDK2 (0.35) | PIM1ALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL20174373 | 0.89 | CYP1A1 (0.36) | PIM1CYP1A2CYP1A1CYP1B1ALDH1A1 | |
| SCHEMBL20174375 | 0.87 | ALDH1A1 (0.34) | PIM1CYP1A2CYP1A1CYP1B1ALDH1A1 | |
| SCHEMBL20174380 | 0.86 | CYP1A1 (0.39) | PIM1CYP1A2CYP1A1CYP1B1ALDH1A1 | |
| SCHEMBL20174369 | 0.86 | CYP1A1 (0.39) | PIM1CYP1A2CYP1A1CYP1B1ALDH1A1 | |
| SCHEMBL20174384 | 0.86 | CYP1A1 (0.40) | PIM1CYP1A2CYP1A1CYP1B1ALDH1A1 | |
| SCHEMBL22326560 | 0.85 | CYP1A1 (0.37) | PIM1CYP1A2CYP1A1CYP1B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10738034-B2 | Spiro compound and organic light-emitting device comprising same | LG CHEM, LTD. (KR) | 2020-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10738034-B2 | Spiro compound and organic light-emitting device comprising same | CRY1, NR2E3, ERG | PIM1 2804/4885CYP1A2 436/4885NPC1 2492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.