Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 11/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 9/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20174492 | 0.88 | CYP1A1 (0.40) | S1PR5S1PR4ALOX5 | |
| SCHEMBL20174497 | 0.88 | CYP1A1 (0.40) | S1PR5S1PR4ALOX5 | |
| SCHEMBL20174489 | 0.85 | S1PR5 (0.37) | S1PR5S1PR4ALOX5CNR1CNR2 | |
| SCHEMBL20174470 | 0.84 | MEN1 (0.32) | — | |
| SCHEMBL20199165 | 0.83 | S1PR5 (0.35) | S1PR5S1PR4 | |
| SCHEMBL20174491 | 0.82 | S1PR5 (0.37) | S1PR5S1PR4ALOX5HSD17B1HSD17B2 | |
| SCHEMBL20174514 | 0.82 | ADORA2A (0.30) | ALOX5 | |
| SCHEMBL20174506 | 0.82 | CYP1A1 (0.37) | S1PR5S1PR4 | |
| SCHEMBL20174452 | 0.81 | L3MBTL1 (0.34) | ALOX5 | |
| SCHEMBL22326568 | 0.81 | CYP1A1 (0.36) | S1PR5S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10738034-B2 | Spiro compound and organic light-emitting device comprising same | LG CHEM, LTD. (KR) | 2020-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10738034-B2 | Spiro compound and organic light-emitting device comprising same | CRY1, NR2E3, ERG | S1PR5 3034/4885S1PR4 1783/4885ALOX5 2705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.